SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019
Patient-reported outcomes as predictors of survival in patients with bowel cancer: a systematic review.
Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- The prognostic value of patient-reported outcomes in allogeneic hematopoietic stem cell transplantation: exploratory analysis of a randomized nutrition intervention trial.Annals of hematology · 2023Trial
- Trial
- Patient-Reported Outcomes Predict Progression-Free Survival of Patients with Advanced Breast Cancer Treated with Abemaciclib.The oncologist · 2021Trial
- Trial
- Artificial Intelligence for Identifying Patient-Reported Outcome and Experience Measures in Oncology: Retrospective Cross-Sectional Study Using ClinicalTrials.gov.Journal of medical Internet research · 2026Article
- A Short Patient-Reported Outcome Measure for Oral Anticancer Agents: Multicenter Observational Study.JMIR formative research · 2026Observational
- The relationship between the latent profiles of cancer-related fatigue characteristics and exercise adherence in colorectal cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Stakeholder perspectives on the use of patient-reported outcome measures in colorectal cancer survivorship care in general practice: qualitative study using interviews.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Fatigue in long-term cancer survivors: prevalence, associated factors, and mortality. A prospective population-based study.British journal of cancer · 2025Article
- Are measures and related symptoms of cachexia recorded as outcomes in gastrointestinal cancer chemotherapy clinical trials?Journal of cachexia, sarcopenia and muscle · 2024Article
- Racial and ethnic disparities in self-reported general and mental health status among colorectal cancer survivors: impact of sociodemographic factors and implications for mortality-a SEER-CAHPS study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Review
- Trajectories and risk factors of fatigue following colorectal cancer diagnosis.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2023Article
- The association between sarcopenia and quality of life in patients undergoing colorectal cancer surgery: an exploratory study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Could existing infrastructure for using patient-reported outcomes as quality measures also be used for individual care in patients with colorectal cancer?BMC health services research · 2021Article
- Clinicians' knowledge and attitudes towards patient reported outcomes in colorectal cancer care - insights from qualitative interviews.BMC health services research · 2021Observational
- Prediction of mortality in metastatic colorectal cancer in a real-life population: a multicenter explorative analysis.BMC cancer · 2020Article
- Patient-reported outcomes and experiences from the perspective of colorectal cancer survivors: meta-synthesis of qualitative studies.Journal of patient-reported outcomes · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe prognostic value of patient-reported outcomes (PROs) has been determined in some cancers, but a focussed review in colorectal cancer (CRC) has not yet been conducted. We systematically reviewed PRO predictors of CRC patient survival.
methodsWe searched four electronic databases (from inception to May 2018), reference lists and professional organisations to identify studies reporting pre-treatment PRO predictors of overall survival (OS) or progression-free survival (PFS) in CRC identified through univariate or multivariate models. Two reviewers independently applied inclusion criteria and extracted data on study characteristics, median and 1-year survival rates, PROs assessed and model results.
resultsIn 25 of 27 studies (n = 12,544), at least one PRO was significantly associated with survival. Physical functioning, fatigue, pain and appetite loss predicted OS more often than other PROs in metastatic disease (19/27 studies). One study explored PRO predictors in early-stage CRC, finding emotional well-being and mood predicted OS. In mixed-stage samples (7/27 studies), physical functioning predicted OS more often than other PROs. Few studies modelled PFS, for which few PROs had predictive value.
conclusionsPhysical and psychological functioning, pain, fatigue and appetite loss had prognostic significance above and beyond clinical predictors in CRC. Routine monitoring of these PROs may allow earlier detection and amelioration of problems, which may improve quality of life and perhaps extend survival. More research is needed to determine prognostic value of PROs in early-stage CRC, and prognostic significance of changes in PRO scores.
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