ArticleOpen forum infectious diseases2019
Seroprevalence of Strongyloides stercoralis and Evaluation of Universal Screening in Kidney Transplant Candidates: A Single-Center Experience in Houston (2012-2017).
Article in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 29 citations in OpenAlex.
- Prevalence of Strongyloides stercoralis in haemodialysis patients in Vienna.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026Article
- Article
- The evaluation of kidney transplant candidates prior to waitlisting: a scoping review.Clinical kidney journal · 2025Article
- A 5-year single-center review ofProceedings (Baylor University. Medical Center) · 2025Article
- Indolent infections in patients with hematologic malignancy: A single-center experience screening for tuberculosis and strongyloidiasis prior to cytotoxic therapy in Boston.Leukemia research reports · 2024Article
- Evaluation of a Geographic Screening Protocol for Chronic Parasitic Infections Before Kidney Transplant: An Institutional Experience in Minnesota.The American journal of tropical medicine and hygiene · 2022Article
- Seroprevalence of Strongyloides stercoralis infection in a South Indian adult population.PLoS neglected tropical diseases · 2022Article
- Seroprevalence of Strongyloides infection among steroid recipients in a tertiary care centre in North India.Le infezioni in medicina · 2022Article
- Strongyloides Superinfection After Liver Transplantion.Digestive diseases and sciences · 2021Article
- Answer to May 2021 Photo Quiz.Journal of clinical microbiology · 2021Article
- Diagnosis of severe respiratory infections in immunocompromised patients.Intensive care medicine · 2020Review
- [Screening for strongyloidiasis in Spain in the context of the SARS-CoV-2 pandemic: Results of a survey on diagnosis and treatment].Enfermedades infecciosas y microbiologia clinicaArticle
- A 5-year single-center review ofProceedings (Baylor University. Medical Center)Article
- Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDisseminated strongyloidiasis in solid organ transplant recipients is a rare but devastating infection. In our center, we implemented a universal screening of all candidates for kidney transplantation. We assessed the seroprevalence and utility of universal screening for strongyloidiasis in our center.
methodsPatients were identified from our transplant referral list (from July 2012 to June 2017). Demographics, pretransplant laboratory, and serological screenings were retrospectively collected. For Strongyloides-seropositive (SSp) patients, data on travel history, symptoms, treatment, and stool ova and parasite examinations were extracted. Logistic regression and multiple imputation for missing data were performed.
resultsA total of 1689 patients underwent serological screening, of whom 168 (9.9%) were SSp. Univariate analysis revealed that SSp patients had higher rates of eosinophilia, diabetes mellitus, latent tuberculosis and were likely to be either Hispanic or Asian (P < .05). In multivariate analysis, eosinophilia (P = .01), diabetes mellitus (P = .02), and Asian race (P = .03) were associated with being SSp, but 45 (27%) of the SSp patients did not have any of these 3 factors, and 18 SSp patients (11%) had no epidemiological risk factors. All patients received ivermectin, and none developed disseminated strongyloidiasis. Of patients who underwent serological screening on multiple occasions, 6.8% seroconverted while waiting for kidney transplantation.
conclusionsWe found a high rate of Strongyloides seropositivity among our kidney transplantation candidates. No epidemiological risk factors effectively predicted SSp status in our population, and universal screening identified a large number of patients without such factors. Serial screening should be considered when a long wait time is expected before transplantation.
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