Evidence map›Paper›PMID 31363762›Full record

ArticleOpen forum infectious diseases2019

Beta-Lactam/Beta-Lactamase Inhibitor Therapy for Potential AmpC-Producing Organisms: A Systematic Review and Meta-Analysis.

Matthew P Cheng, Robyn S Lee, Alexandre P Cheng, Samuel De L'étoile-Morel, Koray Demir, Cedric P Yansouni, Patrick Harris, Emily G Mcdonald, Todd C Lee

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Matthew P ChengDivision of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Robyn S LeeCenter for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.
Alexandre P ChengMeinig School of Biomedical Engineering, Cornell University, Ithaca, New York.
Samuel De L'étoile-MorelDivision of Infectious Diseases, Department of Medicine, McGill University Health Centre, Montreal, Canada.
Koray DemirClinical Practice Assessment Unit, Department of Medicine, McGill University Health Centre, Montreal, Canada.
Cedric P YansouniDivision of Infectious Diseases, Department of Medicine, McGill University Health Centre, Montreal, Canada.
Patrick HarrisUniversity of Queensland, UQ Centre for Clinical Research, Brisbane, Australia.
Emily G McdonaldClinical Practice Assessment Unit, Department of Medicine, McGill University Health Centre, Montreal, Canada.
Todd C LeeDivision of Infectious Diseases, Department of Medicine, McGill University Health Centre, Montreal, Canada.
McGill University Health Centre · CABrigham and Women's Hospital · USCenter for Disease Dynamics, Economics & Policy · USCornell University · USThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The optimal treatment for potential AmpC-producing Enterobacteriaceae, including Serratia, Providencia, Citrobacter, Enterobacter, and Morganella species, remains unknown. An updated systematic review and meta-analysis of studies comparing beta-lactam/beta-lactamase inhibitors with carbapenems in the treatment of bloodstream infections with these pathogens found no significant difference in 30-day mortality (OR, 1.13; 95% CI, 0.58 - 2.20).

Indexed as

ampCbacteremiaBeta-Lactambeta-lactamasecarbapenem

Identifiers

PMID31363762
PMCPMC6656656
OpenAlexW2944946867

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.