Evidence map›Paper›PMID 31363458›Full record

ArticleWorld journal of orthopedics2019

Platelet-rich plasma for muscle injuries: A systematic review of the basic science literature.

Kyle N Kunze, Charles P Hannon, Jared D Fialkoff, Rachel M Frank, Brian J Cole

Open access · hybridAbstract read
In one paragraph

Article in World journal of orthopedics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Efficacy of platelet-rich plasma in grade 2 hamstring muscle injuries: results from a randomized controlled trial.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Trial
  3. Does Changes in the Muscles Beneath the Submucosal Tissues Necessitate a Novel Strategy in the Medical Management of OSMF: A Systematic Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  4. Article
  5. Review
  6. Medial Gastrocnemius Strain: Clinical Aspects and Algorithmic Approach.Medical journal of the Islamic Republic of Iran · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kyle N KunzeDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612, United States. kyle_n_kunze@rush.edu.
Charles P HannonDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612, United States.
Jared D FialkoffDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612, United States.
Rachel M FrankDepartment of Orthopedic Surgery, University of Colorado School of Medicine, Boulder, CO 80309, United States.
Brian J ColeDepartment of Orthopedics, Rush University Medical Center, Chicago, IL 60612, United States.
Rush University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlatelet-rich plasma (PRP) is an increasingly used biologic adjunct for muscle injuries, as it is thought to expedite healing. Despite its widespread use, little is known regarding the mechanisms by which PRP produces its efficacious effects in some patients.

aimTo clarify the effects of PRP on muscular pathologies at the cellular and tissue levels by evaluating the basic science literature.

methodsA systematic review of PubMed/MEDLINE and EMBASE databases was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and checklist. Level III

resultsTwenty-three studies were included (15

conclusionThe basic science literature on the use of PRP in muscle pathology demonstrates that PRP treatment confers several potentially beneficial effects on healing in comparison to controls. Future research is needed to determine optimal cytology, dosing, timing, and delivery methods of PRP for muscle pathologies.

Indexed as

Basic scienceInjuryMuscleMusculoskeletalPlatelet rich plasma

Identifiers

PMID31363458
PMCPMC6650633
OpenAlexW2958560893

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.