ReviewWorld journal of orthopedics2019
Randomised controlled trial of triclosan coated
Review in World journal of orthopedics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Triclosan-Containing Sutures for the Prevention of Surgical Site Infection: A Systematic Review and Meta-Analysis.JAMA network open · 2025Pooled it
- Effect of barbed versus standard sutures on wound complications in total knee arthroplasty: A meta-analysis.International wound journal · 2023Pooled it
- Plus Sutures for preventing surgical site infection: a systematic review of clinical outcomes with economic and environmental models.BMC surgery · 2023Pooled it
- The role of triclosan-coated suture in preventing surgical infection: A meta-analysis.Joint diseases and related surgery · 2023Pooled it
- Current reported practices in surgical antibiotic prophylaxis and infection prevention in primary arthroplasty: an open web-based survey among orthopedic specialists in Türkiye.BMC musculoskeletal disorders · 2026Article
- Consensus document on the management of wound closure in orthopaedic surgery.EFORT open reviews · 2025Review
- Article
- Use of monofilament sutures and triclosan coating to protect against surgical site infections in spinal surgery: a laboratory-based study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Article
- Bone mineral as a drug-seeking moiety and a waste dump.Bone & joint research · 2020Article
- A comparison between barbed suture and conventional suture in total knee arthroplasty: a systematic review and meta-analysis.Arthroplasty (London, England) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTriclosan-coated vicryl plus suture (Ethicon, Inc.) was developed to reduce microbial colonisation during surgical procedures. However, its effect on wound healing and surgical site infections remain unclear after hip and knee arthro-plasty surgery.
aimTo determine the effect of triclosan-coated sutures (TCS)
methodsA single-centred, double-blind randomised controlled trial (RCT) was undertaken. We randomly allocated patients to receive either the triclosan-coated sutures (TCS vicryl plus) or non-coated sutures (NCS vicryl) during the closure of unilateral primary hip and knee arthroplasties. We utilised the ASEPSIS wound scoring system to evaluate wound healing for the first 6 weeks post-operatively.
resultsOne hundred and fifty patients undergoing primary total hip or knee arthroplasty over a one-year period were included. Eighty-one were randomised to the TCS group and 69 to the NCS group. Despite no statistically significant difference in the ASEPSIS scores among the study groups (
conclusionNo clear advantage was demonstrated for using the TCS. However, larger multi-centred RCTs are required to validate their use in hip and knee arthroplasty surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.