Evidence map›Paper›PMID 31363372›Full record

ArticleExperimental and therapeutic medicine2019

Candidate genes and pathways associated with brain metastasis from lung cancer compared with lymph node metastasis.

Xuelian Zhao, Nan Wang, Tungamirai Chidanguro, Huanyu Gu, Yi Li, Huiru Cao, Pushuai Wen, Fu Ren

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Immune related biomarkers for cancer metastasis to the brain.Experimental hematology & oncology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xuelian ZhaoDepartment of Pathophysiology, Jinzhou Medical University, Jinzhou, Liaoning 121001, P.R. China.
Nan WangDepartment of Pathophysiology, Jinzhou Medical University, Jinzhou, Liaoning 121001, P.R. China.
Tungamirai ChidanguroDepartment of Pathophysiology, Jinzhou Medical University, Jinzhou, Liaoning 121001, P.R. China.
Huanyu GuDepartment of Pathophysiology, Jinzhou Medical University, Jinzhou, Liaoning 121001, P.R. China.
Yi LiDepartment of Pathophysiology, Jinzhou Medical University, Jinzhou, Liaoning 121001, P.R. China.
Huiru CaoDepartment of Pathophysiology, Jinzhou Medical University, Jinzhou, Liaoning 121001, P.R. China.
Pushuai WenDepartment of Pathophysiology, Jinzhou Medical University, Jinzhou, Liaoning 121001, P.R. China.
Fu RenBiological Anthropology Institute, Jinzhou Medical University, Jinzhou, Liaoning 121001, P.R. China.
Jinzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain metastasis from lung cancer (BMLC) is one of the common types of metastasis associated with poor prognosis. The aim of the present study was to elucidate the underlying molecular mechanisms of BMLC. The mRNA microarray dataset GSE18549 was downloaded from the Gene Expression Omnibus database. The Limma package of R was used to screen the differentially expressed genes (DEGs). Based on the DAVID database, functional and pathway enrichment analyses of DEGs were performed. Furthermore, the protein-protein interaction (PPI) network was predicted using the STRING database and visualized with Cytoscape software. In addition, hub genes and significant modules were selected based on the network. A total of 190 DEGs with log

Indexed as

bioinformatics analysisbrain metastasisDAVID databasedifferentially expressed geneslung cancer

Identifiers

PMID31363372
PMCPMC6614716
OpenAlexW2953560896

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.