Evidence map›Paper›PMID 31363110›Full record

ArticleScientific reports2019

Application of a Limit-Cycle Oscillator Model for Prediction of Circadian Phase in Rotating Night Shift Workers.

Julia E Stone, Xavier L Aubert, Henning Maass, Andrew J K Phillips, Michelle Magee, Mark E Howard, Steven W Lockley, Shantha M W Rajaratnam, Tracey L Sletten

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Julia E StoneCRC for Alertness, Safety and Productivity, Melbourne, Victoria, Australia.
Xavier L AubertPhilips Research, Eindhoven, The Netherlands.
Henning MaassPhilips Research, Eindhoven, The Netherlands.
Andrew J K PhillipsCRC for Alertness, Safety and Productivity, Melbourne, Victoria, Australia.
Michelle MageeCRC for Alertness, Safety and Productivity, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0001-6642-0882
Mark E HowardCRC for Alertness, Safety and Productivity, Melbourne, Victoria, Australia.
Steven W LockleyCRC for Alertness, Safety and Productivity, Melbourne, Victoria, Australia.
Shantha M W RajaratnamCRC for Alertness, Safety and Productivity, Melbourne, Victoria, Australia.
Tracey L SlettenCRC for Alertness, Safety and Productivity, Melbourne, Victoria, Australia. tracey.sletten@monash.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Practical alternatives to gold-standard measures of circadian timing in shift workers are needed. We assessed the feasibility of applying a limit-cycle oscillator model of the human circadian pacemaker to estimate circadian phase in 25 nursing and medical staff in a field setting during a transition from day/evening shifts (diurnal schedule) to 3-5 consecutive night shifts (night schedule). Ambulatory measurements of light and activity recorded with wrist actigraphs were used as inputs into the model. Model estimations were compared to urinary 6-sulphatoxymelatonin (aMT6s) acrophase measured on the diurnal schedule and last consecutive night shift. The model predicted aMT6s acrophase with an absolute mean error of 0.69 h on the diurnal schedule (SD = 0.94 h, 80% within ±1 hour), and 0.95 h on the night schedule (SD = 1.24 h, 68% within ±1 hour). The aMT6s phase shift from diurnal to night schedule was predicted to within ±1 hour in 56% of individuals. Our findings indicate the model can be generalized to a shift work setting, although prediction of inter-individual variability in circadian phase shift during night shifts was limited. This study provides the basis for further adaptation and validation of models for predicting circadian phase in rotating shift workers.

Indexed as

Circadian RhythmHealth PersonnelModels, TheoreticalActivity CyclesAdultFemaleHumansMaleMelatoninMiddle AgedShift Work Schedule6-sulfatoxymelatoninMelatonin

Identifiers

PMID31363110
PMCPMC6667480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.