Evidence map›Paper›PMID 31363109›Full record

ArticleScientific reports2019

Cooperative and distinct functions of MK2 and MK3 in the regulation of the macrophage transcriptional response to lipopolysaccharide.

Christian Ehlting, Julia Rex, Ute Albrecht, René Deenen, Christopher Tiedje, Karl Köhrer, Oliver Sawodny, Matthias Gaestel, Dieter Häussinger, Johannes Georg Bode

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Christian EhltingClinic for Gastroenterology, Hepatology and Infectiology, University Hospital, Medical Faculty, Heinrich Heine University of Düsseldorf, Düsseldorf, Germany.
Julia RexInstitute for System Dynamics, University of Stuttgart, Stuttgart, Germany.ORCID http://orcid.org/0000-0002-8189-9243
Ute AlbrechtClinic for Gastroenterology, Hepatology and Infectiology, University Hospital, Medical Faculty, Heinrich Heine University of Düsseldorf, Düsseldorf, Germany.
René DeenenBiological and Medical Research Center (BMFZ), Genomics & Transcriptomics Laboratory, Heinrich Heine University of Düsseldorf, Düsseldorf, Germany.
Christopher TiedjeInstitute of Cell Biochemistry, Hannover Medical School, Hannover, Germany.
Karl KöhrerBiological and Medical Research Center (BMFZ), Genomics & Transcriptomics Laboratory, Heinrich Heine University of Düsseldorf, Düsseldorf, Germany.
Oliver SawodnyInstitute for System Dynamics, University of Stuttgart, Stuttgart, Germany.
Matthias GaestelInstitute of Cell Biochemistry, Hannover Medical School, Hannover, Germany.ORCID http://orcid.org/0000-0002-4944-4652
Dieter HäussingerClinic for Gastroenterology, Hepatology and Infectiology, University Hospital, Medical Faculty, Heinrich Heine University of Düsseldorf, Düsseldorf, Germany.
Johannes Georg BodeClinic for Gastroenterology, Hepatology and Infectiology, University Hospital, Medical Faculty, Heinrich Heine University of Düsseldorf, Düsseldorf, Germany. Johannes.Bode@med.uni-duesseldorf.de.
Düsseldorf University Hospital · DEHeinrich Heine University Düsseldorf · DEUniversity of Stuttgart · DEMedizinische Hochschule Hannover · DEUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The p38

Indexed as

MAP Kinase Signaling SystemTranscriptomeAnimalsCells, CulturedChemokine CXCL2Interferon-gammaInterleukin-4 Receptor alpha SubunitInterleukinsIntracellular Signaling Peptides and ProteinsLipopolysaccharidesMacrophagesMAP-Kinase-Activated Kinase 2MiceMice, Inbred C57BLp38 Mitogen-Activated Protein KinasesProtein Serine-Threonine KinasesChemokine CXCL2Il4ra protein, mouseInterferon-gammaInterleukin-4 Receptor alpha SubunitInterleukinsIntracellular Signaling Peptides and ProteinsLipopolysaccharidesMAP-Kinase-Activated Kinase 2MAP-kinase-activated kinase 3p38 Mitogen-Activated Protein KinasesProtein Serine-Threonine KinasesReceptors, Cell Surface

Identifiers

PMID31363109
PMCPMC6667695
OpenAlexW2965381051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.