Evidence map›Paper›PMID 31363087›Full record

ArticleNature communications2019

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G Guy Bushkin, David Pincus, Jeffrey T Morgan, Kris Richardson, Caroline Lewis, Sze Ham Chan, David P Bartel, Gerald R Fink

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 81 citations in OpenAlex.

  1. Article
  2. Seven wonders of RNA modification biology.RNA (New York, N.Y.) · 2026
    Review
  3. Article
  4. mRNA mGenome biology · 2025
    Article
  5. Article
  6. Loss ofInternational journal of molecular sciences · 2025
    Article
  7. Article
  8. Article
  9. NCells · 2024
    Article
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  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

G Guy BushkinWhitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA. gbushkin@wi.mit.edu.ORCID http://orcid.org/0000-0001-7437-5874
David PincusWhitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.ORCID http://orcid.org/0000-0002-9651-6858
Jeffrey T MorganWhitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
Kris RichardsonWhitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
Caroline LewisWhitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
Sze Ham ChanWhitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
David P BartelWhitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
Gerald R FinkWhitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA. gfink@wi.mit.edu.
Whitehead Institute for Biomedical Research · USHoward Hughes Medical Institute · USUniversity of Chicago · US

Funding

PRE-DOCTORAL TRAINING IN THE BIOLOGICAL SCIENCEST32GM007287 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELL, STEPHEN P., KEATING, AMY E · 1985 to 2019
$40.8M
Post-transcriptional gene regulationR35GM118135 · NIGMS · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI DAVID P BARTEL · 2016 to 2026
$10.7M
REGULATION OF HISTIDINE BIOSYNTHESIS IN YEASTR01GM035010 · NIGMS · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI FINK, GERALD R · 1985 to 2016
$9.9M
Quantitative approaches to reveal the homeostatic control mechanisms of stress reDP5OD017941 · OD · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI PINCUS, DAVID · 2013 to 2017
$2.4M
Roles for mRNA methylation and lncRNA in Candida mating and pathogenicityF32GM108201 · NIGMS · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI BUSHKIN, GARY GUY · 2014 to 2016
$164k
NIGMS NIH HHS F32 GM108201NIGMS NIH HHS R01 GM035010NIGMS NIH HHS R35 GM118135NIGMS NIH HHS T32 GM007287NIH HHS DP5 OD017941
6 · The paper itself

Abstract

Despite the vast number of modification sites mapped within mRNAs, known examples of consequential mRNA modifications remain rare. Here, we provide multiple lines of evidence to show that Ime4p, an N6-methyladenosine (m

Indexed as

3' Untranslated RegionsAdenosineGene Expression Regulation, FungalMeiosisMethylationRepressor ProteinsRNA, MessengerSaccharomyces cerevisiaeSaccharomyces cerevisiae Proteins3' Untranslated RegionsAdenosineN-methyladenosineRepressor ProteinsRME1 protein, S cerevisiaeRNA, MessengerSaccharomyces cerevisiae Proteins

Identifiers

PMID31363087
PMCPMC6667471
OpenAlexW2966853058

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.