Evidence map›Paper›PMID 31363055›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

UvrD helicase activation by MutL involves rotation of its 2B subdomain.

Yerdos A Ordabayev, Binh Nguyen, Alexander G Kozlov, Haifeng Jia, Timothy M Lohman

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Structural basis for dimerization and activation of UvrD-family helicases.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. "Helicase" Activity promoted through dynamic interactions between a ssDNA translocase and a diffusing SSB protein.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  13. Article
  14. Review
  15. Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Regulation of E. coli Rep helicase activity by PriC.Journal of molecular biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yerdos A OrdabayevDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110.
Binh NguyenDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110.
Alexander G KozlovDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110.
Haifeng JiaDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110.
Timothy M LohmanDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110 lohman@biochem.wustl.edu.
Washington University in St. Louis · US

Funding

HELICASE-CATALYZED DNA UNWINDINGR01GM045948 · NIGMS · WASHINGTON UNIVERSITY · PI LOHMAN, TIMOTHY M · 1991 to 2020
$9.2M
NIGMS NIH HHS R01 GM045948
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA-Binding ProteinsDNA HelicasesDNA RepairDNA, Single-StrandedEscherichia coliEscherichia coli ProteinsFluorescence Resonance Energy TransferKineticsMutL ProteinsProtein ConformationProtein DomainsSingle Molecule ImagingDNA-Binding ProteinsDNA HelicasesDNA, Single-StrandedEscherichia coli ProteinsMutL protein, E coliMutL Proteinsrep protein, E coliUvrD protein, E coliactivationconformational selectionhelicasemismatch repairsingle molecule fluorescence

Identifiers

PMID31363055
PMCPMC6697780
OpenAlexW2964762483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.