Evidence map›Paper›PMID 31362969›Full record

Trial reportBMJ open2019

Short-term weight gain among preschool children in rural Burkina Faso: a secondary analysis of a randomised controlled trial.

Elena G Dennis, Ali Sie, Lucienne Ouermi, Clarisse Dah, Charlemagne Tapsoba, Pascal Zabre, Till Bärnighausen, Kieran S O'Brien, Elodie Lebas, Jeremy D Keenan and 1 more

Registry-linked trialOpen access · goldAbstract readClinical Trial, Phase IVRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03187834 (Antibiotic Resistance and Microbiome in Children Aged 6-59 Months in Nouna, Burkina Faso), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03187834 phase4completednot on this map

Antibiotic Resistance and Microbiome in Children Aged 6-59 Months in Nouna, Burkina Faso

TypeinterventionalSponsorUniversity of California, San FranciscoRan2017 to 2019Enrolled252ConditionsChild DevelopmentArmsAzithromycin, Amoxicillin, Cotrimoxazole, Placebo
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Rapid Reduction ofThe American journal of tropical medicine and hygiene · 2020
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 4 countries.

Elena G DennisFrancis I Proctor Foundation, University of California, San Francisco, California, USA.
Ali SieCentre de Recherche en Sante de Nouna, Nouna, Burkina Faso.
Lucienne OuermiCentre de Recherche en Sante de Nouna, Nouna, Burkina Faso.
Clarisse DahCentre de Recherche en Sante de Nouna, Nouna, Burkina Faso.
Charlemagne TapsobaCentre de Recherche en Sante de Nouna, Nouna, Burkina Faso.
Pascal ZabreCentre de Recherche en Sante de Nouna, Nouna, Burkina Faso.
Till BärnighausenInstitute of Public Health, Heidelberg University, Heidelberg, Germany.
Kieran S O'BrienFrancis I Proctor Foundation, University of California, San Francisco, California, USA.
Elodie LebasFrancis I Proctor Foundation, University of California, San Francisco, California, USA.
Jeremy D KeenanFrancis I Proctor Foundation, University of California, San Francisco, California, USA.ORCID 0000-0002-7118-1457
Catherine E OldenburgFrancis I Proctor Foundation, University of California, San Francisco, California, USA catherine.oldenburg@ucsf.edu.ORCID 0000-0002-0763-399X
Centre de Recherche en Santé de Nouna · BFUniversity of California, San Francisco · USHeidelberg University · DE

Funding

The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
NIMH NIH HHS R25 MH083620
6 · The paper itself

Abstract

objectivesNutrition has profound effects on children's health outcomes and is linked to weight gain and cognitive development. We used data from a randomised controlled trial to evaluate the prospective associations between dietary, socioeconomic and demographic factors and short-term weight gain during the lean season in a rural area of Burkina Faso.

designProspective cohort data arising from a randomised controlled trial of the effect of antibiotic distribution on child growth and intestinal microbial diversity.

settingTwo rural communities in Nouna District, Burkina Faso.

participants246 children aged 6-59 months living in the study communities were enrolled in the study. PRIMARY AND SECONDARY OUTCOME MEASURES: Anthropometric measurements, including weight and height, were obtained at baseline and 1 month.

resultsOf 246 children, the median weight for wasted children at baseline (weight-for-height z-score <-2) was 9.7 kg (IQR 8.65-10.8) and the weight of non-wasted children was 12.8 kg (IQR 10.9-14.75). Food insecurity was significantly associated with decreased weight gain velocity (mean difference -0.03 g/kg/day, 95% CI -0.06 to -0.006, p=0.04).

conclusionExperiences of household food insecurity before the beginning of the lean season were associated with decreased weight gain in children in rural Burkina Faso during the lean season, although the mean difference was small. Understanding the relationship between timing of food insecurity and anthropometric outcomes may help to develop policies and health programme that address both of these issues. TRIAL REGISTRATION NUMBER: NCT03187834.

Indexed as

Child DevelopmentNutritional StatusWeight GainBurkina FasoChild, PreschoolFemaleFood SupplyHumansInfantMaleProspective StudiesRegression AnalysisRural PopulationBurkina Fasofood insecuritynutritional status

Identifiers

PMID31362969
PMCPMC6677972
OpenAlexW2966390052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.