Evidence map›Paper›PMID 31362961›Full record

ArticleBMJ open2019

Are socioeconomic inequalities in the incidence of small-for-gestational-age birth narrowing? Findings from a population-based cohort in the South of England.

Sam Wilding, Nida Ziauddeen, Paul Roderick, Dianna Smith, Debbie Chase, Nick Macklon, Nuala McGrath, Mark Hanson, Nisreen A Alwan

Abstract readMulticenter Study
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sam WildingSchool of Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Nida ZiauddeenSchool of Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.ORCID 0000-0002-8964-5029
Paul RoderickSchool of Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Dianna SmithGeography & Environment, University of Southampton, Southampton, UK.
Debbie ChasePublic Health, Southampton City Council, Southampton, UK.
Nick MacklonDepartment of Obstetrics and Gynaecology, University of Copenhagen, Roskilde, Denmark.
Nuala McGrathSchool of Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Mark HansonInstitute of Developmental Sciences, Academic Unit of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.
Nisreen A AlwanSchool of Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.ORCID 0000-0002-4134-8463

Funding

Academy of Medical Sciences HOP001\1060British Heart Foundation RG/15/17/31749Department of Health RP-2017-08-ST2-008Wellcome Trust
6 · The paper itself

Abstract

objectivesTo investigate socioeconomic inequalities, using maternal educational attainment, maternal and partner employment status, and lone motherhood indicators, in the risk of small-for-gestational-age (SGA) births, their time trend, potential mediation by maternal smoking and body mass index, and effect modification by parity.

designPopulation-based birth cohort using routine antenatal healthcare data.

settingBabies born at University Hospital Southampton, UK, between 2004 and 2016.

participants65 909 singleton live births born to mothers aged ≥18 years between 24-week and 42-week gestation.

main outcome measuresSGA (birth weight <10th percentile for others born at the same number of completed weeks compared with 2013/2014 within England and Wales).

resultsBabies born to mothers educated up to secondary school level (adjusted OR (aOR) 1.32, 99% CI 1.19 to 1.47), who were unemployed (aOR 1.27, 99% CI 1.16 to 1.38) or with unemployed partners (aOR 1.27, 99% CI 1.13 to 1.43), were at greater risk of being SGA. There was no statistically significant change in the magnitude of this risk difference by these indicators over time between 2004 and 2016, as estimated by linear interactions with year of birth. Babies born to lone mothers were not at higher risk compared with partnered mothers after adjusting for maternal smoking (aOR 1.05, 99% CI 0.93 to 1.20). The inverse association between maternal educational attainment and SGA risk appeared greater in multiparous (aOR 1.40, 99% CI 1.10 to 1.77) compared with primiparous women (aOR 1.28, 99% CI 1.12 to 1.47), and the reverse was true for maternal and partner's unemployment where the association was stronger in primiparous women.

conclusionsSocioeconomic inequalities in SGA risk by educational attainment and employment status are not narrowing over time, with differences in association strength by parity. The greater SGA risk in lone mothers was potentially explained by maternal smoking. Preventive interventions should target socially disadvantaged women, including preconception and postpartum smoking cessation to reduce SGA risk.

Indexed as

Infant, Small for Gestational AgeAdolescentAdultEnglandFemaleFollow-Up StudiesHumansIncidenceInfant, NewbornMalePopulation SurveillancePregnancyPremature BirthRetrospective StudiesRisk FactorsSocioeconomic Factorspublic healthsmall for gestational agesocial medicinesocioeconomic inequalities

Identifiers

PMID31362961
PMCPMC6678068

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.