ArticleGenome research2019
Identifying loci under positive selection in complex population histories.
Article in Genome research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Unlocking Ethiopia's genomic landscape and its global significance: a call for inclusive genomics research.Human genomics · 2026Review
- Leveraging graphical model techniques to study evolution on phylogenetic networks.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Identifying Significant SNPs of the Total Number of Piglets Born and Their Relationship with Leg Bumps in Pigs.Biology · 2024Article
- Adaptive Evolution of Two Distinct Adaptive Haplotypes of Neanderthal Origin at the Immunoglobulin Heavy-chain Locus in East Asian and European Populations.Molecular biology and evolution · 2024Article
- Genomic evidence for human-mediated introgressive hybridization and selection in the developed breed.BMC genomics · 2024Article
- A graph-based genome and pan-genome variation of the model plant Setaria.Nature genetics · 2023Article
- Genome-wide scans for selective sweeps using convolutional neural networks.Bioinformatics (Oxford, England) · 2023Article
- Article
- Locus-level antagonistic selection shaped the polygenic architecture of human complex diseases.Human genetics · 2022Article
- Disentangling Signatures of Selection Before and After European Colonization in Latin Americans.Molecular biology and evolution · 2022Article
- The genomic signatures of natural selection in admixed human populations.American journal of human genetics · 2022Article
- Detecting Selection in Multiple Populations by Modeling Ancestral Admixture Components.Molecular biology and evolution · 2022Article
- The immunogenetic impact of European colonization in the Americas.Frontiers in genetics · 2022Review
- Article
- Article
- Genome Analysis Traces Regional Dispersal of Rice in Taiwan and Southeast Asia.Molecular biology and evolution · 2021Article
- How natural selection shapes genetic differentiation in the MHC region: A case study with Native Americans.Human immunology · 2021Article
- Article
- Evolutionary genetics of skin pigmentation in African populations.Human molecular genetics · 2021Review
- Adaptive Divergence under Gene Flow along an Environmental Gradient in Two Coexisting Stickleback Species.Genes · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Detailed modeling of a species' history is of prime importance for understanding how natural selection operates over time. Most methods designed to detect positive selection along sequenced genomes, however, use simplified representations of past histories as null models of genetic drift. Here, we present the first method that can detect signatures of strong local adaptation across the genome using arbitrarily complex admixture graphs, which are typically used to describe the history of past divergence and admixture events among any number of populations. The method-called graph-aware retrieval of selective sweeps (
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