Evidence map›Paper›PMID 31362754›Full record

ArticleParasites & vectors2019

Regional and local temporal trends in the prevalence of canine heartworm infection in the contiguous United States: 2012-2018.

Stella W Self, Cassan N Pulaski, Christopher S McMahan, D Andrew Brown, Michael J Yabsley, Jenna R Gettings

Abstract read
In one paragraph

Article in Parasites & vectors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  6. Article
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  8. Review
  9. Article
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  11. Fluralaner (BravectoParasites & vectors · 2023
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  12. Article
  13. Article
  14. Treatment of dogs with BravectoParasites & vectors · 2023
    Article
  15. Article
  16. Geographical analysis of seroprevalence ofCurrent research in parasitology & vector-borne diseases · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Stella W SelfSchool of Mathematical and Statistical Sciences, Clemson University, Clemson, SC, 29634, USA.
Cassan N PulaskiDepartment of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, 70803, USA.
Christopher S McMahanSchool of Mathematical and Statistical Sciences, Clemson University, Clemson, SC, 29634, USA.
D Andrew BrownSchool of Mathematical and Statistical Sciences, Clemson University, Clemson, SC, 29634, USA.
Michael J YabsleySoutheastern Cooperative Wildlife Disease Study, Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602, USA.
Jenna R GettingsSoutheastern Cooperative Wildlife Disease Study, Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602, USA. jenna.gettings@uga.edu.ORCID http://orcid.org/0000-0003-2540-2172

Funding

National Institutes of Health Al121351National Science Foundation CMMI-1563435National Science Foundation EEC-1744497National Science Foundation OIA-1826715
6 · The paper itself

Abstract

backgroundCanine heartworm disease is a potentially fatal disease for which treatment is financially burdensome for many pet owners. Prevention is strongly advocated by the veterinary community along with routine testing for infection during annual wellness examinations. Despite the availability of efficacious chemoprophylaxis, recent reports have suggested that the incidence of heartworm disease in domestic dogs is increasing.

resultsUsing data from tests for heartworm infection in the USA from January 2012 through September 2018, a Bayesian spatio-temporal binomial regression model was used to estimate the regional and local temporal trends of heartworm infection prevalence. The area with the largest increase in regional prevalence was found in the Lower Mississippi River Valley. Regional prevalence increased throughout the southeastern states and northward into Illinois and Indiana. Local (county-level) prevalence varied across the USA, with increasing prevalence occurring along most of the Atlantic coast, central United States, and western states. Clusters of decreasing prevalence were present along the Mississippi Alluvial Plain (a historically endemic area), Oklahoma and Kansas, and Florida.

conclusionsCanine heartworm infection prevalence is increasing in much of the USA, both regionally and locally, despite veterinarian recommendations on prevention and testing. Additional steps should be taken to protect dogs, cats and ferrets. Further work is needed to identify the driving factors of the locally decreasing prevalence present along the Mississippi Alluvial plain, Florida, and other areas.

Indexed as

AnimalsAntigens, HelminthDirofilaria immitisDirofilariasisDog DiseasesDogsFemaleGeographyHospitals, AnimalIncidenceMississippiModels, StatisticalPetsPrevalenceSpatio-Temporal AnalysisUnited StatesAntigens, HelminthHeartwormTemporal trendsUSA

Identifiers

PMID31362754
PMCPMC6668072

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.