Evidence map›Paper›PMID 31362449›Full record

ArticlePolymers2019

Use of Polyphenol Tannic Acid to Functionalize Titanium with Strontium for Enhancement of Osteoblast Differentiation and Reduction of Osteoclast Activity.

Chris Steffi, Zhilong Shi, Chee Hoe Kong, Sue Wee Chong, Dong Wang, Wilson Wang

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chris SteffiDepartment of Orthopaedic Surgery, National University of Singapore, NUHS Tower Block Level 11, 1E Kent Ridge Road, Singapore 119228, Singapore.
Zhilong ShiDepartment of Orthopaedic Surgery, National University of Singapore, NUHS Tower Block Level 11, 1E Kent Ridge Road, Singapore 119228, Singapore.
Chee Hoe KongDepartment of Orthopaedic Surgery, National University of Singapore, NUHS Tower Block Level 11, 1E Kent Ridge Road, Singapore 119228, Singapore.
Sue Wee ChongDepartment of Orthopaedic Surgery, National University of Singapore, NUHS Tower Block Level 11, 1E Kent Ridge Road, Singapore 119228, Singapore.
Dong WangDepartment of Orthopaedic Surgery, National University of Singapore, NUHS Tower Block Level 11, 1E Kent Ridge Road, Singapore 119228, Singapore.
Wilson WangDepartment of Orthopaedic Surgery, National University of Singapore, NUHS Tower Block Level 11, 1E Kent Ridge Road, Singapore 119228, Singapore. doswangw@nus.edu.sg.
National University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Implant anchorage remains a challenge, especially in porous osteoporotic bone with high osteoclast activity. The implant surface is modified with osteogenic molecules to stimulate osseointegration. Strontium (Sr) is known for its osteogenic and anti-osteoclastogenic effects. In this study, Sr was immobilized on a titanium (Ti) surface using bioinspired polyphenol tannic acid (pTAN) coating as an ad-layer (Ti-pTAN). Two separate coating techniques were employed for comparative analysis. In the first technique, Ti was coated with a tannic acid solution containing Sr (Ti-pTAN-1Stp). In the second method, Ti was first coated with pTAN, before being immersed in a SrCl

Indexed as

osteoblastsosteoclastsOsteoporosispolyphenol tannic acidstrontiumtitanium

Identifiers

PMID31362449
PMCPMC6723407
OpenAlexW2966415777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.