Evidence map›Paper›PMID 31362398›Full record

ReviewMicroorganisms2019

The Genetic Basis of Toxin Biosynthesis in Dinoflagellates.

Arjun Verma, Abanti Barua, Rendy Ruvindy, Henna Savela, Penelope A Ajani, Shauna A Murray

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
  2. Review
  3. Microbial Metabolism: Primary and Secondary Metabolites.Progress in molecular and subcellular biology · 2026
    Review
  4. Article
  5. Bioactive Polyketides fromMarine drugs · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. The Common SunstarMarine drugs · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Arjun VermaClimate Change Cluster, University of Technology Sydney, Sydney 2007, Australia. Arjun.verma@uts.edu.au.ORCID 0000-0003-0119-9915
Abanti BaruaClimate Change Cluster, University of Technology Sydney, Sydney 2007, Australia.
Rendy RuvindyClimate Change Cluster, University of Technology Sydney, Sydney 2007, Australia.
Henna SavelaFinnish Environment Institute, Marine Research Centre, 00790 Helsinki, Finland.
Penelope A AjaniClimate Change Cluster, University of Technology Sydney, Sydney 2007, Australia.ORCID 0000-0001-5364-9936
Shauna A MurrayClimate Change Cluster, University of Technology Sydney, Sydney 2007, Australia.
University of Technology Sydney · AUFinnish Environment Institute · FI

Funding

Australian Research Council FT120100704
6 · The paper itself

Abstract

In marine ecosystems, dinoflagellates can become highly abundant and even dominant at times, despite their comparatively slow growth rates. One factor that may play a role in their ecological success is the production of complex secondary metabolite compounds that can have anti-predator, allelopathic, or other toxic effects on marine organisms, and also cause seafood poisoning in humans. Our knowledge about the genes involved in toxin biosynthesis in dinoflagellates is currently limited due to the complex genomic features of these organisms. Most recently, the sequencing of dinoflagellate transcriptomes has provided us with valuable insights into the biosynthesis of polyketide and alkaloid-based toxin molecules in dinoflagellate species. This review synthesizes the recent progress that has been made in understanding the evolution, biosynthetic pathways, and gene regulation in dinoflagellates with the aid of transcriptomic and other molecular genetic tools, and provides a pathway for future studies of dinoflagellates in this exciting omics era.

Indexed as

alkaloidsdinoflagellatespolyketidestoxinstranscriptomics

Identifiers

PMID31362398
PMCPMC6722697
OpenAlexW2965742803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.