Evidence map›Paper›PMID 31362365›Full record

ArticleInternational journal of molecular sciences2019

ESRP1 Induces Cervical Cancer Cell G1-Phase Arrest Via Regulating Cyclin A2 mRNA Stability.

Zhi-Hong Chen, Ya-Jie Jing, Jian-Bo Yu, Zai-Shu Jin, Zhu Li, Ting-Ting He, Xiu-Zhen Su

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
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  6. ESRP1 exerts anti-tumor role by promoting ferroptosis in diffuse-type gastric cancer.Journal of experimental & clinical cancer research : CR · 2025
    Article
  7. Review
  8. Review
  9. Upregulated expression ofJournal of gastrointestinal oncology · 2024
    Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhi-Hong ChenSchool of Basic Medicine, Youjiang Medical University for Nationalities, No. 98 Chengxiang Road, Baise 533000, China. chenzh808@126.com.
Ya-Jie JingSciences Research Center, Youjiang Medical University for Nationalities, No. 98 Chengxiang Road, Baise 533000, China.
Jian-Bo YuHeilongjiang Province Key Laboratory of Cancer Prevention and Treatment, Mudanjiang Medical University, No. 3, Tongxiang Street, Mudanjiang 157011, China.
Zai-Shu JinHeilongjiang Province Key Laboratory of Cancer Prevention and Treatment, Mudanjiang Medical University, No. 3, Tongxiang Street, Mudanjiang 157011, China.
Zhu LiHeilongjiang Province Key Laboratory of Cancer Prevention and Treatment, Mudanjiang Medical University, No. 3, Tongxiang Street, Mudanjiang 157011, China.
Ting-Ting HeSciences Research Center, Youjiang Medical University for Nationalities, No. 98 Chengxiang Road, Baise 533000, China.
Xiu-Zhen SuSciences Research Center, Youjiang Medical University for Nationalities, No. 98 Chengxiang Road, Baise 533000, China.
Affiliated Hospital of Youjiang Medical University for Nationalities · CNMudanjiang Medical University · CN

Funding

National Natural Science Foundation of China 31860313the Natural Science Foundation of Heilongjiang Province of China LC2016040
6 · The paper itself

Abstract

Accumulating evidence indicates that epithelial splicing regulatory protein 1 (ESRP1) can inhibit the epithelial-to-mesenchymal transition (EMT), thus playing a central role in regulating the metastatic progression of tumors. However, it is still not clear whether ESRP1 directly influences the cell cycle, or what the possible underlying molecular mechanisms are. In this study, we showed that ESRP1 protein levels were significantly correlated with the Ki-67 proliferative index (

Indexed as

Gene Expression Regulation, NeoplasticRNA Stability3' Untranslated RegionsCdc20 ProteinsCell Line, TumorCyclin A2FemaleG1 Phase Cell Cycle CheckpointsHumansImmunohistochemistryModels, BiologicalProtein BindingRNA-Binding ProteinsRNA, MessengerUterine Cervical Neoplasms3' Untranslated RegionsCDC20 protein, humanCdc20 ProteinsCyclin A2ESRP1 protein, humanRNA-Binding ProteinsRNA, Messengercell proliferationcyclin A2ESRP1G1-phase arrestmRNA stability

Identifiers

PMID31362365
PMCPMC6695732
OpenAlexW2964777672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.