Evidence map›Paper›PMID 31361973›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Imbalance of autophagy and apoptosis in intestinal epithelium lacking the vitamin D receptor.

Rong Lu, Yong-Guo Zhang, Yinglin Xia, Jun Sun

Open access · greenAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 70 citations in OpenAlex.

  1. Role of Bile Acid Receptors in Non-Infectious Diarrhea: A Narrative Review.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Review
  2. Observational
  3. Review
  4. Review
  5. Article
  6. Emerging role of vitamin DAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2024
    Article
  7. Article
  8. Journal of fungi (Basel, Switzerland) · 2023
    Article
  9. Vitamin D Promotes Mucosal Barrier System of Fish Skin Infected withInternational journal of molecular sciences · 2023
    Article
  10. ERRα protects against sepsis-induced acute lung injury in rats.Molecular medicine (Cambridge, Mass.) · 2023
    Article
  11. Myeloid vitamin D receptor regulates Paneth cells and microbial homeostasis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  12. Vitamin DCell biology and toxicology · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Lipophilic and Hydrophilic Compounds fromLife (Basel, Switzerland) · 2022
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rong LuDepartment of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
Yong-Guo ZhangDepartment of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
Yinglin XiaDepartment of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
Jun SunDepartment of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
University of Illinois Chicago · US

Funding

How Vitamin D Receptor Influences Intestinal BarriersR01DK114126 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Jun Sun · 2018 to 2026
$3.0M
Vitamin D Receptor Regulation of Microbiota in Intestinal EpitheliaR01DK105118 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SUN, JUN · 2016 to 2020
$1.8M
NIDDK NIH HHS R01 DK105118NIDDK NIH HHS R01 DK114126
6 · The paper itself

Abstract

Apoptosis and autophagy are dynamic processes that determine the fate of cells. Vitamin D receptor (VDR) deficiency in the intestine leads to abnormal Paneth cells and impaired autophagy function. Here, we will elucidate the mechanisms of the intestinal epithelial VDR regulation of autophagy and apoptosis. We used

Indexed as

AnimalsApoptosisAutophagyAutophagy-Related ProteinsCarrier ProteinsColonIntestinal MucosaIntestinesMice, TransgenicPaneth CellsReceptors, CalcitriolSignal TransductionAutophagy-Related ProteinsCarrier ProteinsReceptors, CalcitriolBeclin-1colonoidsenteroidsinflammationVDR

Identifiers

PMID31361973
PMCPMC6902693
OpenAlexW2965044191

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.