Evidence map›Paper›PMID 31361714›Full record

Trial reportMedicine and science in sports and exercise2020

Effects of Lifestyle Physical Activity on Vascular Function in Asymptomatic Peripheral Arterial Disease.

Steve Laslovich, Brent A Alvar, Matthew Allison, Mitchell J Rauh

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Medicine and science in sports and exercise, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Steve LaslovichUniversity of St. Augustine for Health Sciences, San Marcos, CA.
Brent A AlvarPoint Loma Nazarene University, Point Loma, CA.
Matthew AllisonDepartment of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA.
Mitchell J RauhDoctor of Physical Therapy Program, School of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA.
Point Loma Nazarene University · USSan Diego State University · USUniversity of California, San Diego · USUniversity of St. Augustine for Health Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to examine the effects of a 12-wk in-home self-monitored physical activity (PA) program targeting a combination of lifestyle PA program on changes in endothelial reactivity, arterial stiffness, sedentary behaviors, and upright and stepping activities in individuals with asymptomatic peripheral arterial disease (APAD).

methodsParticipants (n = 38) with APAD (ages 52-87 yr) were randomized to attention control (AC) or a PA sedentary reduction (PASR) group using an interactive online 3-month program focusing on increasing lifestyle PA and decreasing sedentary behaviors. The ActivPal™ PA monitor was used to measure postural and stepping parameters. Endothelial reactivity (peripheral arterial tone-reactive hyperemia index [PAT-RHI]) and augmentation index (AIx) were measured using the EndoPAT™ system at baseline and 3 months.

resultsThe PASR group significantly decreased daily sit/lie hours (-0.80 ± 0.87 vs 0.18 ± 0.77 P = 0.001), increased sit-to-stand transitions per day (7.1 ± 10.5 vs -1.4 ± 5.71, P < 0.001), and increased daily step counts (2814 ± 1753 vs 742 ± 1321, P < 0.001). The PASR group also increased steps per day accumulated within specific cadence bands 61-80 steps per minute (1252 ± 447 vs 177 ± 359, P < 0.001), 81-100 steps per minute band (919 ± 511 vs -98 ± 697, P < 0.001), and within the 101-120 steps per minute band (415 ± 625 vs -327 ± 467, P < 0.001) versus the AC group. PAT-RHI significantly increased in the PASR group (0.179 ± 0.180 vs 0.0.044 ± 0.101, P = 0.019), whereas no significant changes were observed in PAT-AIx.

conclusionsModest improvements in microvascular reactivity, PA, sedentary behavior, but not arterial stiffness were demonstrated after a 12-wk intervention targeting sedentary behavior reduction and increased lifestyle PA in individuals with APAD.

Indexed as

ExerciseHealthy LifestyleAgedAged, 80 and overAsymptomatic DiseasesEndothelium, VascularExercise TherapyFemaleFitness TrackersHumansMaleMicrocirculationMiddle AgedPeripheral Arterial DiseaseSedentary BehaviorVascular Stiffness

Identifiers

PMID31361714
OpenAlexW2964692141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.