ArticleOtology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology2019
Histopathology of Inner Ear Malformations: Potential Pitfalls for Cochlear Implantation.
Article in Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 19 citations in OpenAlex.
- Improved assessment of the cochlear implant and temporal bone structures with ultra-high resolution photon-counting detector CT compared to conventional CT systems.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- An artificial neuromorphic interface for auditory restoration.Nature materials · 2026Article
- Cochlear Implants in Inner Ear Malformations-Considerations Regarding the Role of Imaging in Preoperative Evaluation.Healthcare (Basel, Switzerland) · 2026Article
- Evolving trends in cochlear implant reimplantation: An analysis of causes and outcomes at a tertiary referral cohort.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Inner Ear Malformations with Transitional Forms between Cochlear Hypoplasia and Common Cavity: Embryological Insights, Imaging Characteristics, and Cochlear Implantation Strategies.Journal of otology · 2026Article
- Abnormalities of the Facial Nerve in Temporal Bones With Inner Ear Malformations.Laryngoscope investigative otolaryngology · 2025Article
- Estimation of outer-wall length in optimizing cochlear implantation in malformed inner ears.Scientific reports · 2024Article
- A Spectrum of Intraoperative and Postoperative Complications of Cochlear Implants: A Critical Review.Cureus · 2022Review
- Effect of inner ear malformations on intraoperative ECAP thresholds and postoperative auditory performance.Laryngoscope investigative otolaryngology · 2022Article
- A novel method of identifying inner ear malformation types by pattern recognition in the mid modiolar section.Scientific reports · 2021Article
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Authors and funding
6 authors at 4 institutions in 4 countries.
Funding
Abstract
hypothesisThe presence of bony inner ear malformations may associate with a number of anatomical abnormalities affecting the middle ear structures. Those malformations may create pitfalls and complications for cochlear implantation.
backgroundInner ear malformations associate with varying degrees of hearing loss, and frequently require cochlear implantation for hearing rehabilitation. Therefore, the abnormalities affecting the middle- and inner-ear structures may increase the risk of surgical complications.
methodsWe examined 38 human temporal bones from donors with bony inner ear malformations. Using light microscopy, we analyzed the presence of abnormalities in the structures of the middle- and inner-ear.
resultsOur collection comprises of 38 specimens with inner-ear malformations (cochlear aplasia, n = 3; cochlear hypoplasia, n = 30; incomplete partition, n = 3; isolated vestibular malformation, n = 2). The anatomy of the middle ear was abnormal in most temporal bones with cochlear aplasia, cochlear hypoplasia, and incomplete partition type I (40%-100%). Some of those abnormalities (hypoplastic or obliterated mastoid, 55.2%; aplastic or obliterated round window, 71.0%; aberrant course of the facial nerve, 36.8%) may hinder the access to the round window using the conventional facial recess approach for cochlear implantation. The cochlear nerve and associated bony structures (internal auditory canal and bony canal for cochlear nerve) were normal in 71.0% of all temporal bones with inner ear malformations.
conclusionEach different type of malformation may create specific surgical challenges to surgeons. Comprehensive preoperative imaging is fundamental toward the surgical success of cochlear implants in patients with malformations. Alternatives to circumvent those middle- and inner-ear abnormalities and potential complications are further discussed.
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