Evidence map›Paper›PMID 31361435›Full record

ArticleJBRA assisted reproduction2019

Can we predict the IVF/ICSI live birth rate?

José Luis Metello, Claudia Tomás, Pedro Ferreira

Open access · greenAbstract read
In one paragraph

Article in JBRA assisted reproduction, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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  8. Clinical data-based modeling of IVF live birth outcome and its application.Reproductive biology and endocrinology : RB&E · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

José Luis MetelloDivision of Reproductive Endocrinology and Infertility, Garcia de Orta Hospital, Almada, Portugal.
Claudia TomásDivision of Reproductive Endocrinology and Infertility, Garcia de Orta Hospital, Almada, Portugal.
Pedro FerreiraDivision of Reproductive Endocrinology and Infertility, Garcia de Orta Hospital, Almada, Portugal.
Hospital Garcia de Orta · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo find a pretreatment predictor for achieving a live birth. Assisted reproduction technology with IVF/ICSI is the ultimate chance for some couples to conceive a child. The expectations are high and it is important to give them a realistic perspective about the chances of achieving a live birth.

methodsA retrospective cohort study of all IVF/ICSI cycles performed in our center between 2012 and 2016. We considered only those cycles with a live birth delivery after 24 weeks, or cycles with no surplus embryos left. The following data was evaluated: AMH; AFC; age; BMI; previous diagnosis; type of treatment; number of previous deliveries; ethnicity, smoking status. Univariate and multivariate analysis were used to examine the association of live birth with baseline patient characteristics. We determined the odds-ratio for all the statistically significant variables (p<0.05), in a multivariate model. The results are presented according to the predictors founded.

results739 cycles were evaluated: 9.1% were canceled; 10.2% did not have oocytes; 15.6% did not have D2 embryos; 31.4% achieved a live birth. The univariate analysis revealed statistically significant differences regarding AMH, AFC and women's age between couples with and without a live birth (p<0.001), and the cause of infertility. We found no association with live births in other variables. These variables were categorized and used in a multivariate analysis.

conclusionAge, AMH, AFC and cause, when sub-classified, are independently associated with the results of an IVF/ICSI treatment. These results enable couples to face real expectations in their particular scenario.

Indexed as

Birth RateFertilization in VitroLive BirthSperm Injections, IntracytoplasmicAdolescentAdultFemaleHumansInfant, NewbornInfertilityMaleOvarian FollicleOvulation InductionParityPregnancyPregnancy Rateageantimullerian hormoneantral follicle countin vitro fertilizationlive-birth ratepredictor

Identifiers

PMID31361435
PMCPMC6798599
OpenAlexW2969472339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.