Evidence map›Paper›PMID 31361146›Full record

ArticleMolecular pharmaceutics2019

In Vivo Antibacterial Efficacy of Nitric Oxide-Releasing Hyperbranched Polymers against

Lei Yang, Li Jing, Yizu Jiao, Lufei Wang, Julie T Marchesan, Steven Offenbacher, Mark H Schoenfisch

Open access · greenAbstract read
In one paragraph

Article in Molecular pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Nitric oxide-releasing prodrug for the treatment of complexAntimicrobial agents and chemotherapy · 2024
    Article
  4. Potent, Broad-Spectrum Antimicrobial Effects ofACS applied bio materials · 2022
    Article
  5. Review
  6. Antibacterial action of nitric oxide-releasing hyperbranched polymers against ex vivo dental biofilms.Dental materials : official publication of the Academy of Dental Materials · 2020
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Li Jing
Yizu Jiao
Lufei WangOral and Craniofacial Biomedicine Program, School of Dentistry , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.
Julie T Marchesan
Steven Offenbacher
Mark H SchoenfischORCID 0000-0002-2212-0658
University of North Carolina at Chapel Hill · US

Funding

Nitric oxide-releasing dendrimers for the treatment of periodontal diseaseR01DE025207 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SCHOENFISCH, MARK H · 2015 to 2019
$1.6M
IFI16 is a Periodontitis Modulating ProteinK01DE027087 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MARCHESAN, JULIE TERESA · 2017 to 2022
$833k
NIDCR NIH HHS K01 DE027087NIDCR NIH HHS R01 DE025207
6 · The paper itself

Abstract

The in vivo antibacterial activity of NO-releasing hyperbranched polymers was evaluated against

Indexed as

AmoxicillinAnimalsAnti-Bacterial AgentsBacteroidaceae InfectionsDisease Models, AnimalEpoxy CompoundsMaleMiceMice, Inbred C57BLMicrobial Sensitivity TestsMicrobial ViabilityNitric OxidePeriodontitisPolyaminesPolymersPorphyromonas gingivalisAmoxicillinAnti-Bacterial AgentsEpoxy CompoundsNitric OxidePoly(amidoamine)PolyaminesPolymerspropylene oxidemurine subcutaneous chamber modelNO-releasing hyperbranched polymersoral health

Identifiers

PMID31361146
PMCPMC6752707
OpenAlexW2949312761

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.