Evidence map›Paper›PMID 31361034›Full record

ArticleClinical cardiology2019

Short-term blood pressure changes have a more strong impact on stroke and its subtypes than long-term blood pressure changes.

Rongrong Guo, Yanxia Xie, Jia Zheng, Yali Wang, Yue Dai, Zhaoqing Sun, Liying Xing, Xingang Zhang, Yingxian Sun, Liqiang Zheng

Abstract readMulticenter Study
In one paragraph

Article in Clinical cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rongrong GuoDepartment of Clinical Epidemiology, Library, Shengjing Hospital of China Medical University, Shenyang, P. R. China.
Yanxia XieDepartment of Clinical Epidemiology, Library, Shengjing Hospital of China Medical University, Shenyang, P. R. China.
Jia ZhengDepartment of Clinical Epidemiology, Library, Shengjing Hospital of China Medical University, Shenyang, P. R. China.
Yali WangDepartment of Clinical Epidemiology, Library, Shengjing Hospital of China Medical University, Shenyang, P. R. China.
Yue DaiDepartment of Clinical Epidemiology, Library, Shengjing Hospital of China Medical University, Shenyang, P. R. China.
Zhaoqing SunDepartment of Cardiology, Shengjing Hospital of China Medical University, Shenyang, P. R. China.
Liying XingInstitute of Chronic Disease, Liaoning Provincial Center for Disease Control and Prevention, Shenyang, P. R. China.
Xingang ZhangDepartment of Cardiology, The First Affiliated Hospital of China Medical University, Shenyang, P. R. China.
Yingxian SunDepartment of Cardiology, Shengjing Hospital of China Medical University, Shenyang, P. R. China.
Liqiang ZhengDepartment of Clinical Epidemiology, Library, Shengjing Hospital of China Medical University, Shenyang, P. R. China.ORCID https://orcid.org/0000-0003-0101-9398

Funding

National Key R&D Program of China #2017YFC1307600National Key R&D Program of China #2018YFC1311600National Nature Science Foundation of China 81773510
6 · The paper itself

Abstract

backgroundElevated blood pressure (BP) is closely related to stroke and its subtypes. However, different time periods changes in BP may result in differential risk of stroke. HYPOTHESIS: Short-term blood pressure changes have a more strong impact on stroke and its subtypes than long-term blood pressure changes.

methodsWe designed the study on the effects of short- (2008-2010) and long-term (2004-2010) BP changes on stroke events (2011-2017), including 22 842 and 28 456 subjects, respectively. The difference in β coefficients between short- and long-term BP changes on the effects of stroke were examined using the Fisher Z test.

resultsDuring a median 12.5-year follow-up period, 1014 and 1505 strokes occurred in short- and long-term groups. In short-term group, going from prehypertension to hypertension, the risk of stroke events increased (stroke: hazard ratio [HR] = 1.537 [1.248-1.894], ischemic stroke: 1.456 [1.134-1.870] and hemorrhagic stroke: 1.630 [1.099-2.415]); going from hypertension to prehypertension, the risk of stroke events decreased (stroke:0.757 [0.619-0.927] and hemorrhagic stroke:0.569 [0.388-0.835]). Similarly, in long-term group, going from prehypertension to hypertension, individuals had an increased risk of stroke (1.291, 1.062-1.569) and hemorrhagic stroke (1.818, 1.261-2.623); going from hypertension to prehypertension, participants had a decreased risk of stroke (0.825, 0.707-0.963) and hemorrhagic stroke (0.777, 0.575-0.949). Furthermore, the effects of BP changes during short-term period on stroke events were greater than that in long-term period.

conclusionsShort- and long-terms BP changes were both associated with the risk of stroke events. Furthermore, short-term BP changes had a stronger impact than did long-term changes on risk of stroke events.

Indexed as

ForecastingBlood PressureBlood Pressure DeterminationChinaFemaleFollow-Up StudiesHumansHypertensionIncidenceMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk FactorsStrokeblood pressureblood pressure changescohort studystroke

Identifiers

PMID31361034
PMCPMC6788570

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.