ArticleJNCI cancer spectrum2019
Delayed Colonoscopy Following a Positive Fecal Test Result and Cancer Mortality.
Article in JNCI cancer spectrum, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Impact of SARS-CoV-2 Pandemic on Colorectal Cancer Screening Delay: Effect on Stage Shift and Increased Mortality.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2021Pooled it
- Longer travel times to acute hospitals are associated with lower likelihood of cancer screening receipt among rural-dwelling adults in the U.S. South.Cancer causes & control : CCC · 2025Article
- Painless colonoscopy: fact or fiction?Clinical endoscopy · 2024Review
- Robotic Colonoscopy and Beyond: Insights into Modern Lower Gastrointestinal Endoscopy.Diagnostics (Basel, Switzerland) · 2023Review
- Comorbidities and Risk Factors of Patients Diagnosed with CRC after Positive Fecal Test in Real Life.Cancers · 2022Article
- Examining the Factors That Affect the Diagnosis of Patients with Positive Fecal Occult Blood Test Results.International journal of environmental research and public health · 2022Article
- The impact of cumulative colorectal cancer screening delays: A simulation study.Journal of medical screening · 2022Article
- Patient Navigation After Positive Fecal Immunochemical Test Results Increases Diagnostic Colonoscopy and Highlights Multilevel Barriers to Follow-Up.Digestive diseases and sciences · 2021Article
- Time to Colonoscopy After Abnormal Stool-Based Screening and Risk for Colorectal Cancer Incidence and Mortality.Gastroenterology · 2021Article
- Aspects of colorectal cancer screening, methods, age and gender.Journal of internal medicine · 2021Review
- Optimal diagnostic accuracy of quantitative faecal immunochemical test positivity thresholds for colorectal cancer detection in primary health care: A community-based cohort study.United European gastroenterology journal · 2021Article
- Framework and Strategies to Eliminate Disparities in Colorectal Cancer Screening Outcomes.Annual review of medicine · 2021Review
- The Value of Multi-targeted Fecal DNA Methylation Detection for Colorectal Cancer Screening in a Chinese Population.Journal of Cancer · 2021Article
- Impact of colorectal cancer screening participation in remote northern Canada: A retrospective cohort study.World journal of gastroenterology · 2020Article
- Making FIT Count: Maximizing Appropriate Use of the Fecal Immunochemical Test for Colorectal Cancer Screening Programs.Journal of general internal medicine · 2020Article
- A survey on colonoscopy shows poor understanding of its protective value and widespread misconceptions across Europe.PloS one · 2020Article
- Abnormal Colorectal Cancer Test Follow-Up: A Quality Improvement Initiative at a Federally Qualified Health Center.Journal of primary care & community healthArticle
- Evolving Dynamics of Colorectal Cancer in High Socio-Demographic Regions.Cancer control : journal of the Moffitt Cancer CenterArticle
- A 5-year evaluation of early-and late-onset sporadic colorectal cancer screening in central Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA fecal test followed by diagnostic colonoscopy for a positive result is a widely endorsed screening strategy for colorectal cancer (CRC). However, the relationship between the time delay from the positive test to the follow-up colonoscopy and CRC mortality has not been established.
methodsFrom a population-based screening program, we identified CRC patients newly diagnosed from 2005 through 2015 by a positive fecal occult test followed by a colonoscopy. The primary outcome measure was CRC-specific mortality according to four categories for the time elapsed between the positive result and the subsequent colonoscopy.
resultsThe 1749 patients underwent colonoscopies within 0-3 months (n = 981, 56.1%), 4-6 months (n = 307, 17.5%), 7-12 months (n = 157, 9.0%), and later than 12 months (n = 304, 17.4%). CRC-specific deaths according to exposure groups were: 13.8% (135 of 981) for 0-3 months, 10.7% (33 of 307) for 4-6 months (crude hazards ratio [HR] = 0.74, 95% confidence interval [CI] = 0.51 to 1.14), 11.5% (18 of 157) for 7-12 months (crude HR = 0.83, 95% CI = 0.51 to 1.42), and 22.7% (69 of 304) for longer than 12 months (crude HR = 1.40, 95% CI = 1.04 to 1.90). The only variable that was associated with mortality risk was the number of positive slides (
conclusionsAmong screen-diagnosed CRC patients, performance of colonoscopy more than 12 months after the initial positive fecal occult blood test was associated with more advanced disease and higher mortality due to CRC.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.