Evidence map›Paper›PMID 31360792›Full record

ReviewIBRO reports2019

Neuromodulation with electromagnetic stimulation for seizure suppression: From electrode to magnetic coil.

Hui Ye, Stephanie Kaszuba

Abstract readReview
In one paragraph

Review in IBRO reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Ephaptic conduction in tonic-clonic seizures.Frontiers in neurology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Non-pharmacological Interventions for Intractable Epilepsy.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hui YeDepartment of Biology, Loyola University Chicago, Chicago, 1032 W. Sheridan Rd., IL, 60660, United States.
Stephanie KaszubaChicago Medical School, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Rd., North Chicago, IL, 60064, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-invasive brain tissue stimulation with a magnetic coil provides several irreplaceable advantages over that with an implanted electrode, in altering neural activities under pathological situations. We reviewed clinical cases that utilized time-varying magnetic fields for the treatment of epilepsy, and the safety issues related to this practice. Animal models have been developed to foster understanding of the cellular/molecular mechanisms underlying magnetic control of epileptic activity. These mechanisms include (but are not limited to) (1) direct membrane polarization by the magnetic field, (2) depolarization blockade by the deactivation of ion channels, (3) alteration in synaptic transmission, and (4) interruption of ephaptic interaction and cellular synchronization. Clinical translation of this technology could be improved through the advancement of magnetic design, optimization of stimulation protocols, and evaluation of the long-term safety. Cellular and molecular studies focusing on the mechanisms of magnetic stimulation are of great value in facilitating this translation.

Indexed as

4-AP, 4-aminopyridineAnimal modelsCD50, convulsant doseCellular mechanismsDBS, deep brain stimulationEcoG, electrocorticographyEEG, electroencephalographyELF-MF, extremely low frequency magnetic fieldsEpilepsyGABA, gamma-aminobutyric acidHFS, high frequency stimulationKA, kainic acidLD50, lethal doseLTD, long-term depressionLTP, long-term potentialMagnetic stimulationMEG, magnetoencephalographyMRI, magnetic resonance imagingNMDAR, N-methyl-d-aspartate receptorPTZ, pentylenetetrazolREM, rapid eye movementrTMS, repetitive transcranial magnetic stimulationSMF, static magnetic fieldtDCS, transcranial direct-current stimulationTES, transcranial electrical stimulationTLE, temporal lobe epilepsyTMS, transcranial magnetic stimulation

Identifiers

PMID31360792
PMCPMC6639724

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.