ArticleTranslational vision science & technology2019
Weekly Changes in Axial Length and Choroidal Thickness in Children During and Following Orthokeratology Treatment With Different Compression Factors.
Article in Translational vision science & technology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation of the Effect of Short-term Orthokeratology With Increased Compression Factor on Ocular Parameters
A Monocentre, Randomized, Contralateral Trial to Study the Effect of Temporal Changes in Ocular Biometry of Two Myopia Control Lenses
Who cites it
33 citing papers in PubMed, 69 citations in OpenAlex.
- Defocus incorporated multiple segment spectacle lenses versus orthokeratology lenses for myopia control: a non-inferiority randomised clinical trial.BMC ophthalmology · 2026Trial
- Effect of Duration of Spectacle Lenses With Highly Aspherical Lenslets Wear on Choroidal Thickness in Low-Hyperopic Chinese Children.Translational vision science & technology · 2026Trial
- Effect of spectacle lenses with aspherical lenslets on choroidal thickness in myopic children: a 2-year randomised clinical trial.The British journal of ophthalmology · 2023Trial
- Peripheral refraction, relative peripheral refraction, and axial growth: 18-month data from the randomised study-Clinical study Of Near-sightedness; TReatment with Orthokeratology Lenses (CONTROL study).Acta ophthalmologica · 2023Trial
- Efficacy Comparison of Repeated Low-Level Red Light and Low-Dose Atropine for Myopia Control: A Randomized Controlled Trial.Translational vision science & technology · 2022Trial
- Changes in choroidal and retinal thickness 6 months before and during 18 months of orthokeratology lens treatment in myopic children.Acta ophthalmologica · 2026Article
- Effect of orthokeratology lens wear on axial length elongation in myopic children.Frontiers in medicine · 2026Article
- Efficacy and safety of orthokeratology sequentially combined with escalating atropine concentrations for myopia control in children.Scientific reports · 2025Article
- Baseline ocular biometrics in children with orthokeratology-induced axial length reduction or elongation.BMC ophthalmology · 2025Article
- Early Peripapillary Choroidal Thinning during Myopia Development: A Potential Biomarker for Progressive Myopia Identified in Tree Shrews.Investigative ophthalmology & visual science · 2025Article
- How Have Animal Models Increased our Understanding of Human Myopia?Investigative ophthalmology & visual science · 2025Review
- Axial Length Stabilization or Reduction in over 40% of Patients Wearing Extended Depth-of-Focus Contact Lenses.Journal of clinical medicine · 2025Article
- Analysis of axial shortening induced by orthokeratology lenses and its mechanical mechanisms.PloS one · 2025Article
- Safety, Efficacy, and Visual Performance of an Orthokeratology Lens with Increased Compression Factor.Journal of clinical medicine · 2024Article
- Peripheral Eye Length Evaluation in Myopic Children Undergoing Orthokeratology Treatment for 12 Months Using MRI.Clinical optometry · 2024Article
- Impact of multifocal gas-permeable lens designs on short-term choroidal response, axial length, and retinal defocus profile.International journal of ophthalmology · 2024Article
- Systematic Review of Myopia Progression after Cessation of Optical Interventions for Myopia Control.Journal of clinical medicine · 2023Review
- Defocus incorporated multiple segments (DIMS) spectacle lenses increase the choroidal thickness: a two-year randomized clinical trial.Eye and vision (London, England) · 2023Article
- Choroidal vasculature act as predictive biomarkers of long-term ocular elongation in myopic children treated with orthokeratology: a prospective cohort study.Eye and vision (London, England) · 2023Article
- Changes in Choroidal Thickness and Retinal Activity with a Myopia Control Contact Lens.Journal of clinical medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine the influence of compression factor upon changes in axial length and choroidal thickness during and following orthokeratology treatment.
methodsOrthokeratology lenses of different compression factors (one eye with 0.75 D and the fellow eye with 1.75 D) were randomly assigned to 28 subjects (median [range] age: 9.3 [7.8-11.0] years). Ocular biometrics were measured weekly for 1 month of lens wear and after lens cessation until the refraction stabilized (mean duration: 2.8 ± 0.4 weeks). Changes between eyes, and the associations between axial shortening and choroidal thickening with other ocular biometrics were analyzed.
resultsThere were no significant between-eye differences in the changes of ocular biometrics (all
conclusionsIncreasing the compression factor by 1.00 D did not affect changes in ocular biometrics in short-term orthokeratology. Significant axial shortening and choroidal thickening were observed during early treatment period. Axial shortening could not be entirely explained by central corneal thinning and choroidal thickening, which warrants further investigation. TRANSLATIONAL RELEVANCE: Initial axial shortening in orthokeratology is transient and therefore axial length remains useful for long-term monitoring of axial elongation in children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.