Evidence map›Paper›PMID 31360610›Full record

ArticleBiomedical optics express2019

Longitudinal shear waves for elastic characterization of tissues in optical coherence elastography.

Fernando Zvietcovich, Gary R Ge, Humberto Mestre, Michael Giannetto, Maiken Nedergaard, Jannick P Rolland, Kevin J Parker

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 40 citations in OpenAlex.

  1. Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026
    Review
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  8. Review
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  12. Introduction to optical coherence elastography: tutorial.Journal of the Optical Society of America. A, Optics, image science, and vision · 2022
    Article
  13. Wave-based optical coherence elastography: The 10-year perspective.Progress in biomedical engineering (Bristol, England) · 2022
    Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Fernando ZvietcovichDept. of Electrical & Computer Engineering, University of Rochester, Rochester, NY 14627, USA.
Gary R GeThe Institute of Optics, University of Rochester, Rochester, NY 14627, USA.
Humberto MestreCenter for Translational Neuromedicine, Dept. of Neurosurgery, University of Rochester, Rochester, NY 14642, USA.
Michael GiannettoCenter for Translational Neuromedicine, Dept. of Neurosurgery, University of Rochester, Rochester, NY 14642, USA.
Maiken NedergaardCenter for Translational Neuromedicine, Dept. of Neurosurgery, University of Rochester, Rochester, NY 14642, USA.
Jannick P RollandThe Institute of Optics, University of Rochester, Rochester, NY 14627, USA.
Kevin J ParkerDept. of Electrical & Computer Engineering, University of Rochester, Rochester, NY 14627, USA.
University of Rochester · US

Funding

University of Rochester Mentoring Environment: Nurturing Training Opportunities in Research (UR-MENTOR)T32GM007356 · NIGMS · UNIVERSITY OF ROCHESTER · PI O'BANION, M. KERRY · 1985 to 2023
$15.1M
Para-Vascular Basis of Small Vessel DiseaseR01NS100366 · NINDS · UNIVERSITY OF ROCHESTER · PI NEDERGAARD, MAIKEN · 2016 to 2020
$3.8M
Age and AD related bottlenecks in glymphatic-lymphatic waste transportRF1AG057575 · NIA · UNIVERSITY OF ROCHESTER · PI NEDERGAARD, MAIKEN · 2017 to 2017
$3.2M
Capillary hyperemia in white matter: Novel mechanistic insight and effect of hypertension and agingRF1NS110049 · NINDS · UNIVERSITY OF ROCHESTER · PI NEDERGAARD, MAIKEN, WAN, JIANDI · 2018 to 2018
$2.9M
Glymphatic function in a transgenic rat model of Alzheimer's diseaseR01AG048769 · NIA · UNIVERSITY OF ROCHESTER · PI BENVENISTE, HELENE D, NEDERGAARD, MAIKEN · 2014 to 2018
$1.4M
The H-scan approach to classifying ultrasound echoesR21EB025290 · NIBIB · UNIVERSITY OF ROCHESTER · PI PARKER, KEVIN J · 2018 to 2019
$420k
NIA NIH HHS R01 AG048769NIA NIH HHS RF1 AG057575NIBIB NIH HHS R21 EB025290NIGMS NIH HHS T32 GM007356NINDS NIH HHS R01 NS100366NINDS NIH HHS RF1 NS110049
6 · The paper itself

Abstract

In dynamic optical coherence elastography (OCE), surface acoustic waves are the predominant perturbations. They constrain the quantification of elastic modulus to the direction of wave propagation only along the surface of tissues, and disregard elasticity gradients along depth. Longitudinal shear waves (LSW), on the other hand, can be generated at the surface of the tissue and propagate through depth with desirable properties for OCE: (1) LSW travel at the shear wave speed and can discriminate elasticity gradients along depth, and (2) the displacement of LSW is longitudinally polarized along the direction of propagation; therefore, it can be measured by a phase-sensitive optical coherence tomography system. In this study, we explore the capabilities of LSW generated by a circular glass plate in contact with a sample using numerical simulations and tissue-mimicking phantom experiments. Results demonstrate the potential of LSW in detecting an elasticity gradient along axial and lateral directions simultaneously. Finally, LSW are used for the elastography of

Identifiers

PMID31360610
PMCPMC6640829
OpenAlexW2953916661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.