Evidence map›Paper›PMID 31360601›Full record

ArticleBiomedical optics express2019

Molecular photoacoustic imaging with ultra-small gold nanoparticles.

Sangheon Han, Richard Bouchard, Konstantin V Sokolov

Abstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

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  8. Recent nanotheranostic approaches in cancer research.Clinical and experimental medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sangheon HanDepartment of Bioengineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.
Richard BouchardDepartment of Imaging Physics, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
Konstantin V SokolovDepartment of Bioengineering, Rice University, 6100 Main Street, Houston, TX 77005, USA.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Functional, cellular, and molecular imaging and therapy monitoring using ultrasouR01CA158598 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI EMELIANOV, STANISLAV Y, ESTEVA, FRANCISCO J · 2012 to 2018
$2.8M
iThera Medical Multispectral Optoacoustic Tomography System for Full Body Molecular and Functional Small Animal ImagingS10OD019946 · OD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SOKOLOV, KONSTANTIN V · 2015 to 2015
$502k
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA158598NIH HHS S10 OD019946
6 · The paper itself

Abstract

Gold nanoparticles (AuNPs) below 10 nm in size can undergo renal clearance, which could facilitate their clinical translation. However, due to non-linear, direct relationship between their absorption and size, use of such "ultra-small" AuNPs as contrast agents for photoacoustic imaging (PAI) is challenging. This problem is complicated by the tendency of absorption for ultra-small AuNPs to be below the NIR range, which is optimal for

Identifiers

PMID31360601
PMCPMC6640831

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.