Evidence map›Paper›PMID 31360585›Full record

ArticleTurkish journal of obstetrics and gynecology2019

First trimester complete blood cell indices in early and late onset preeclampsia.

Gökçen Örgül, Duygu Aydın Haklı, Gonca Özten, Erdem Fadiloğlu, Atakan Tanacan, Mehmet Sinan Beksaç

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of obstetrics and gynecology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Systemic and Local Immunological Markers in Preeclampsia.Diagnostics (Basel, Switzerland) · 2025
    Article
  8. Importance of STAT3 signaling in preeclampsia (Review).International journal of molecular medicine · 2025
    Review
  9. Article
  10. Article
  11. Review
  12. Pre-eclampsia.Nature reviews. Disease primers · 2023
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gökçen ÖrgülHacettepe University Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Perinatology, Ankara, Turkey.ORCID https://orcid.org/0000-0003-0578-4230
Duygu Aydın HaklıHacettepe University Faculty of Medicine, Department of Biostatistics, Ankara, Turkey.ORCID https://orcid.org/0000-0002-4475-3288
Gonca ÖztenHacettepe University Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Perinatology, Ankara, Turkey.ORCID https://orcid.org/0000-0001-8951-3037
Erdem FadiloğluHacettepe University Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Perinatology, Ankara, Turkey.ORCID https://orcid.org/0000-0001-7953-2517
Atakan TanacanHacettepe University Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Perinatology, Ankara, Turkey.ORCID https://orcid.org/0000-0001-8209-8248
Mehmet Sinan BeksaçHacettepe University Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Perinatology, Ankara, Turkey.ORCID https://orcid.org/0000-0001-6362-787X
Hacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to compare the first trimester complete blood count (CBC) indices of pregnancies complicated by early-onset preeclampsia (EOPE) or late-onset preeclampsia (LOPE). MATERIAL AND

methodsA retrospective case-control study was conducted with 186 patients. Patients were classified into three subgroups: EOPE, LOPE, and control groups. First trimester CBC results were obtained for each patient. Hemoglobin, hematocrit, red blood cell distribution width, mean corpuscular volume, white blood cell (WBC) count, neutrophil, eosinophil, basophil, lymphocyte, monocyte, mean platelet volume, platelet distribution width, plateletcrit, and platelet count were compared. The neutrophil lymphocyte ratio was calculated by dividing the absolute lymphocyte count by the absolute neutrophil count. The platelet lymphocyte ratio was calculated by dividing the absolute lymphocyte count by the absolute platelet count.

resultsThe total number of cases was 21, 42, and 123, in the EOPE, LOPE, and control groups, respectively. There were statistically significant differences in the total WBC and neutrophil counts between the three groups (both p<0.05). WBC and neutrophil counts were found to be highest in the EOPE group, and the LOPE group had higher levels compared with controls. The optimal cut-off values to predict EOPE for WBC and neutrophil counts were 9.55×10

conclusionIncreased first trimester WBC and neutrophil counts may be predictive for EOPE.

Indexed as

complete blood countEarly onset preeclampsialate onset preeclampsianeutrophil countwhite blood cell count

Identifiers

PMID31360585
PMCPMC6637787
OpenAlexW2958811984

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.