Evidence map›Paper›PMID 31360266›Full record

ArticleDisease markers2019

Expression of B2 Receptor on Circulating CD34-Positive Cells and Outcomes of Myocardial Infarction.

Cong Fu, Yuhan Cao, Yuyu Yao, Shengxing Tang, Qun Fan, Yang Ling

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Cong FuDepartment of Cardiology, Yi Ji Shan Hospital Affiliated to Wan Nan Medical College, China.ORCID https://orcid.org/0000-0002-4306-0594
Yuhan CaoKey Laboratory of Non-Coding RNA Transformation Research of Anhui Higher Education Institution (Wan Nan Medical College), China.
Yuyu YaoDepartment of Cardiology, Zhong Da Hospital Affiliated to Southeast University, China.
Shengxing TangDepartment of Cardiology, Yi Ji Shan Hospital Affiliated to Wan Nan Medical College, China.
Qun FanDepartment of Cardiology, Yi Ji Shan Hospital Affiliated to Wan Nan Medical College, China.
Yang LingDepartment of Cardiology, Yi Ji Shan Hospital Affiliated to Wan Nan Medical College, China.
Wannan Medical College · CNZhongda Hospital Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBradykinin B2 receptor (B2R) is a widely expressed cell surface receptor. The relationship between B2R expression on circulating CD34+ cells and prognosis of myocardial infarction remains unknown.

methodsWe analyzed the expression of B2R on circulating CD34-positive cells and plasma VEGF concentration in 174 myocardial infarction patients. All involved patients were divided into two groups: high B2R group and low B2R group according to the median B2R expression percentage. 48 months of follow-up was performed. The endpoints were heart failure and revascularization.

resultsThe plasma level of VEGF in the low B2R group is 67 ± 12 pg/mL, whereas the high B2R group has significantly elevated VEGF levels of 145 ± 27 pg/mL (

conclusionLow expression of B2R on circulating progenitor cells indicated the poor outcomes of myocardial infarction.

Indexed as

AgedAntigens, CD34BiomarkersCells, CulturedChinaFemaleFollow-Up StudiesHeart FailureHumansIncidenceMaleMyocardial InfarctionMyocardial RevascularizationPrognosisReceptor, Bradykinin B2Signal TransductionAntigens, CD34BiomarkersReceptor, Bradykinin B2Vascular Endothelial Growth Factor AVEGFA protein, human

Identifiers

PMID31360266
PMCPMC6644252
OpenAlexW2958757620

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.