Evidence map›Paper›PMID 31360207›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2019

Reproductive Regulation and Oxidative Stress Alleviation of Chinese Herbal Medicine Therapy in Ovariectomised Mouse Model.

Chung-Hsin Wu, Sheue-Er Wang, Chih-Hsiang Hsu, Yu-Tsen Hsu, Chen-Wen Lu, Wu-Chang Chuang, Ming-Chung Lee

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Protective Effects ofBioMed research international · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Chung-Hsin WuSchool of Life Science, National Taiwan Normal University, Taipei City, Taiwan.ORCID https://orcid.org/0000-0002-4470-2448
Sheue-Er WangPathological Department, Saint Paul's Hospital, Taoyuan City, Taiwan.
Chih-Hsiang HsuSchool of Life Science, National Taiwan Normal University, Taipei City, Taiwan.
Yu-Tsen HsuSchool of Life Science, National Taiwan Normal University, Taipei City, Taiwan.
Chen-Wen LuSchool of Life Science, National Taiwan Normal University, Taipei City, Taiwan.
Wu-Chang ChuangSun Ten Pharmaceutical Co. Ltd., New Taipei City 23143, Taiwan.
Ming-Chung LeeBrion Research Institute of Taiwan, New Taipei City 23143, Taiwan.
National Taiwan Normal University · TWTaoyuan Chang Gung Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Taiwan, the herbal formula B401 is considered as a health supplement for middle-aged women that can alleviate sweating, anxiety, and sleep disorders. However, the relevant mechanisms are still unclear. In this study, we evaluated the beneficial effects of the herbal formula B401 therapy in the reproductive regulation of ovariectomised mice. Female ICR mice were randomised into four groups: wild-type (WT) mice with sham treatment, wild-type mice treated with the herbal formula B401, bilateral ovariectomised (OVX) mice with sham treatment, and bilateral ovariectomised mice treated with the herbal formula B401. Mice were orally given the herbal formula B401 at a dose of 30 mg/kg bw/day for 2 weeks. At the end of oral treatment with sham or the herbal formula B401, levels of reactive oxygen species (ROS), calcium, phosphorus, and estradiol-17

Identifiers

PMID31360207
PMCPMC6642789
OpenAlexW2954061988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.