ArticleArchives of medical science : AMS2019
Etanercept protects ovarian reserve against ischemia/reperfusion injury in a rat model.
Article in Archives of medical science : AMS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 56 citations in OpenAlex.
- Protective Effect of Boric Acid Against 3-NPA-Induced Ovarian Damage.Biological trace element research · 2026Article
- Repurposing rupatadine to attenuate ovarian ischemia reperfusion in rats through modulation of PAF/NF-κB/TNF-α/IL-1β; HIF-1α/VEGF/Caspase 3 signaling pathways.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Upregulation of Foxo3a protects neurons against hypoxia-ischaemia injury.Archives of medical science : AMS · 2026Article
- Toxicological Assessment ofInternational journal of molecular sciences · 2025Article
- The molecular mechanism of the protective effect of tianeptine against ovarian ischemia-reperfusion injury.Scientific reports · 2025Article
- Evaluation of the Cytotoxicity, Genotoxicity and Acute Oral Toxicity ofPharmaceuticals (Basel, Switzerland) · 2025Article
- New Potential Agent in Ovarian Ischemia Reperfusion Injury: Alpha Pinene.Journal of biochemical and molecular toxicology · 2025Article
- Inhibition of glioma cell viability by jatrophone via NF-κB down-regulation and apoptosis inhibitor up-regulation.Archives of medical science : AMS · 2025Article
- mRNA-103 inhibition attenuates autophagy and inflammation in myocardial infarction by regulating the TLR4 pathway.Archives of medical science : AMS · 2025Article
- 3-Acetyl-11-keto-β-boswellic acid inhibits cancer cell invasion and induces apoptosis in breast cancer cells by abrogating the EGFR-mediated PI3K/Akt pathway.Archives of medical science : AMS · 2025Article
- Review
- Protective Effects of Boric Acid Taken in Different Ways on Experimental Ovarian İschemia and Reperfusion.Biological trace element research · 2024Article
- Melatonin inhibits apoptosis and oxidative tissue damage in cisplatin-induced pulmonary toxicity in rats.Archives of medical science : AMS · 2024Article
- miR-223 promotes cartilage differentiation of bone marrow-derived mesenchymal stem cells and protects against osteoarthritis by suppressing NLRP-3 expression.Archives of medical science : AMS · 2024Article
- Network analysis of the effects of long non-coding RNAs in artemisinin treatment of atherosclerosis in APOEArchives of medical science : AMS · 2024Article
- Emodin improves the cardiac function in the rats with chronic heart failure through regulation of the miR-26b-5p/PTEN pathway.Archives of medical science : AMS · 2024Article
- Ovarian reserve in children with juvenile idiopathic arthritis using biologic disease-modifying anti-rheumatic drugs.Clinical rheumatology · 2024Article
- The effects of berberine on ischemia-reperfusion injuries in an experimental model of ovarian torsion.Clinical and experimental reproductive medicine · 2023Article
- The influence of adalimumab treatment on the systemic gene expression in patients with psoriatic arthritis - preliminary report.Archives of medical science : AMS · 2023Article
- Effect of trimetazidine against ovarian ischemia/reperfusion injury in rat model: A new pathway: JAK2/STAT3.Iranian journal of basic medical sciences · 2023Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEtanercept has been widely used in autoimmune diseases for blocking tumor necrosis factor α (TNF-α), which is an inflammatory cytokine. The anti-apoptotic and anti-inflammatory effects of etanercept against ischemia/reperfusion (I/R) injury have been shown for several tissues in rat studies, but to the best of our knowledge, there are no reports on its protective effects following similar injury in ovarian tissue. The aim of this study was to investigate whether etanercept has beneficial effects on ovarian I/R injury, as well as on ovarian reserve. MATERIAL AND
methodsTwenty-four rats were randomly divided into four groups (
resultsTissue GSH and SOD levels were significantly higher, while MDA and MPO levels were significantly lower in the I/R + etanercept group than in the I/R group (
conclusionsEtanercept attenuated inflammation and related oxidative stress and also helped to preserve ovarian reserve following ovarian I/R damage.
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