ArticleArchives of medical science : AMS2019
Effect of caffeine on biomarkers of oxidative stress in lenses of rats with streptozotocin-induced diabetes.
Article in Archives of medical science : AMS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 60 citations in OpenAlex.
- Review
- Effects of a caffeine-based diet on insecticide resistance and longevity in infected Anopheles coluzzii.Parasites & vectors · 2026Article
- Up-regulation of peroxiredoxin 3 by high-risk human papillomavirus in cervical cancer cells.Archives of medical science : AMS · 2026Article
- Effect of thymoquinone on cyclophosphamide-induced injury in the rat urinary bladder.Archives of medical science : AMS · 2026Article
- Caffeine mitigates ROS accumulation and attenuates motor neuron degeneration in the wobbler mouse model of amyotrophic lateral sclerosis.Cell communication and signaling : CCS · 2025Article
- Caffeine and Exercise: A Dual Approach to Combat Cognitive Decline Induced by REM Sleep Deprivation.Molecular neurobiology · 2025Article
- Therapeutic Potential ofAntioxidants (Basel, Switzerland) · 2025Article
- Effect of metformin on the level of aqueous humor inflammatory cytokines in patients with cataract.Scientific reports · 2025Article
- Diabetic Retinopathy - Pathophysiology to Treatment: A Review.Current diabetes reviews · 2025Review
- Important role of long non-coding RNA UBE2R2-AS1 in diabetes-induced renal injury.Archives of medical science : AMS · 2025Article
- Fucoxanthin protects neonatal rat cardiomyocytes and attenuates high glucose-mediated oxidative stress via the AMPK pathway.Archives of medical science : AMS · 2025Article
- Deleterious Effects of Caffeine Consumption on Reproductive Functions of Female Wistar Rats.JBRA assisted reproduction · 2024Article
- Caffeine and Vision: Effects on the Eye.Turkish journal of ophthalmology · 2024Review
- Oxidative Stress in Cataract Formation: Is There a Treatment Approach on the Horizon?Antioxidants (Basel, Switzerland) · 2024Review
- Single Mutations in Cytochrome P450 Oxidoreductase Can Alter the Specificity of Human Cytochrome P450 1A2-Mediated Caffeine Metabolism.Biomolecules · 2023Article
- Dual ABMC endocrine disorders · 2023Article
- Determination of the Anti-Oxidative Stress Mechanism ofACS omega · 2023Article
- Oxidative Stress in the Anterior Ocular Diseases: Diagnostic and Treatment.Biomedicines · 2023Review
- Alpinetin: anti-human gastric cancer potential and urease inhibition activityArchives of medical science : AMS · 2023Article
- Novel green synthesis of silver nanoparticles mediated byArchives of medical science : AMS · 2023Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionOne of the major causes of cataract in diabetes is oxidative stress induced by reactive oxygen species (ROS). Nowadays, new substances with antioxidative properties that may prevent cataract development are needed. One such substance is caffeine - an alkaloid with well-documented antioxidative activity. MATERIAL AND
methodsThe study was conducted on lenses obtained from female rats, divided into 3 groups: control rats; diabetic rats; diabetic rats treated with caffeine at a dose of 20 mg/kg
resultsThe SOD, CAT and GPx activities were found to be higher in the lenses of diabetic rats. There were also increased MDA and AOPP concentrations as well as decreased GSH concentration. The administration of caffeine resulted in decreased activity of SOD, CAT and GPx. The treatment with caffeine also caused an increase of GSH concentration and a decrease of MDA and AOPP concentrations.
conclusionsThe results of the present study may be of relevance in determining the effect of caffeine on the processes induced by ROS
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