Evidence map›Paper›PMID 31360201›Full record

ArticleArchives of medical science : AMS2019

Urotensin II promotes secretion of LTB

Dan Lu, Fen Peng, Jun Li, Jing Zhao, Xiaojin Ye, Binghan Li, Wenhui Ding

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

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  12. Oridonin Alleviates IRI-Induced Kidney Injury by Inhibiting Inflammatory Response of Macrophages via AKT-Related Pathways.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  13. Early and Sustained Increases in Leukotriene BNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Dan LuDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Fen PengDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Jun LiDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Jing ZhaoDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Xiaojin YeDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Binghan LiRenal Division, Peking University First Hospital, Beijing, China.
Wenhui DingDepartment of Cardiology, Peking University First Hospital, Beijing, China.
Peking University First Hospital · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUrotensin II (UII) is an important vasoactive peptide involved in the pathogenesis of atherosclerosis. Monocytes/macrophages play important roles in every step of atherosclerosis. Although UII has a chemoattractant effect on monocytes, it is unclear whether UII regulates inflammatory responses in macrophages. The present study sought to explore whether UII can promote leukotriene B MATERIAL AND

methodsThe mRNA expression level of LTB

resultsUrotensin II promoted LTB

conclusionsUrotensin II may promote 5-lipoxygenase expression and LTB

Indexed as

5-lipoxygenaseinflammationleukotriene B4macrophagesurotensin II

Identifiers

PMID31360201
PMCPMC6657259
OpenAlexW2954131163

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.