Evidence map›Paper›PMID 31360118›Full record

ArticleMediators of inflammation2019

Macrophage Migration Inhibitory Factor Promotes the Interaction between the Tumor, Macrophages, and T Cells to Regulate the Progression of Chemically Induced Colitis-Associated Colorectal Cancer.

Thalia Pacheco-Fernández, Imelda Juárez-Avelar, Oscar Illescas, Luis I Terrazas, Rogelio Hernández-Pando, Carlos Pérez-Plasencia, Emma B Gutiérrez-Cirlos, Federico Ávila-Moreno, Yolanda I Chirino, José Luis Reyes and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

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  9. Isothiocyanate-Rich Extracts from Cauliflower (International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Thalia Pacheco-FernándezBiomedicine Unit, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México (UNAM), Tlalnepantla C.P. 54090, Mexico.ORCID https://orcid.org/0000-0003-2741-0942
Imelda Juárez-AvelarBiomedicine Unit, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México (UNAM), Tlalnepantla C.P. 54090, Mexico.ORCID https://orcid.org/0000-0002-0504-6812
Oscar IllescasBiomedicine Unit, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México (UNAM), Tlalnepantla C.P. 54090, Mexico.ORCID https://orcid.org/0000-0002-7326-5486
Luis I TerrazasBiomedicine Unit, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México (UNAM), Tlalnepantla C.P. 54090, Mexico.ORCID https://orcid.org/0000-0003-1635-9467
Rogelio Hernández-PandoExperimental Pathology Section, National Institute of Medical Sciences and Nutrition "Salvador Zubirán", Tlalpan, C.P. 14000 Mexico city, Mexico.
Carlos Pérez-PlasenciaBiomedicine Unit, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México (UNAM), Tlalnepantla C.P. 54090, Mexico.
Emma B Gutiérrez-CirlosBiomedicine Unit, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México (UNAM), Tlalnepantla C.P. 54090, Mexico.ORCID https://orcid.org/0000-0002-6672-1711
Federico Ávila-MorenoBiomedicine Unit, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México (UNAM), Tlalnepantla C.P. 54090, Mexico.
Yolanda I ChirinoBiomedicine Unit, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México (UNAM), Tlalnepantla C.P. 54090, Mexico.ORCID https://orcid.org/0000-0001-6627-3392
José Luis ReyesBiomedicine Unit, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México (UNAM), Tlalnepantla C.P. 54090, Mexico.
Vilma MaldonadoEpigenetics, National Institute of Genomic Medicine, Tlalpan, C.P 14610 Mexico city, Mexico.
Miriam Rodriguez-SosaBiomedicine Unit, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México (UNAM), Tlalnepantla C.P. 54090, Mexico.ORCID https://orcid.org/0000-0003-2911-9390
Autonomous University of Tlaxcala · MXInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXNational Institute of Genomic Medicine · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colitis-associated colorectal cancer (CRC) development has been shown to be related to chronically enhanced inflammation. Macrophage migration inhibitory factor (MIF) is an inflammatory mediator that favors inflammatory cytokine production and has chemotactic properties for the recruitment of macrophages (Møs) and T cells. Here, we investigated the role of MIF in the inflammatory response and recruitment of immune cells in a murine model of chemical carcinogenesis to establish the impact of MIF on CRC genesis and malignancy. We used BALB/c MIF-knockout (MIF

Indexed as

AnimalsColitisColorectal NeoplasmsDisease ProgressionFemaleFlow CytometryImmunohistochemistryMacrophage Migration-Inhibitory FactorsMacrophagesMiceMice, Inbred BALB CMice, KnockoutT-LymphocytesMacrophage Migration-Inhibitory Factors

Identifiers

PMID31360118
PMCPMC6652048
OpenAlexW2960156386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.