Evidence map›Paper›PMID 31360029›Full record

ReviewJournal of clinical and experimental hepatology

Brain Edema in Chronic Hepatic Encephalopathy.

Cristina Cudalbu, Simon D Taylor-Robinson

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Hepatic encephalopathy.Nature reviews. Disease primers · 2022
    Review
  19. The neurogliovascular unit in hepatic encephalopathy.JHEP reports : innovation in hepatology · 2021
    Review
  20. 2021 ISHEN guidelines on animal models of hepatic encephalopathy.Liver international : official journal of the International Association for the Study of the Liver · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Cristina CudalbuCentre d'Imagerie Biomedicale (CIBM), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Simon D Taylor-RobinsonDivision of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, St Mary's Hospital Campus, Imperial College London, London, United Kingdom.
Centre d'Imagerie BioMedicale · CHSt Mary's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain edema is a common feature associated with hepatic encephalopathy (HE). In patients with acute HE, brain edema has been shown to play a crucial role in the associated neurological deterioration. In chronic HE, advanced magnetic resonance imaging (MRI) techniques have demonstrated that low-grade brain edema appears also to be an important pathological feature. This review explores the different methods used to measure brain edema

Indexed as

1H MRS, proton magnetic resonance spectroscopyADC, apparent diffusion coefficientALF, acute liver failureAQP, aquaporinsBBB, blood-brain barrierBDL, bile duct ligationbrain edemachronic hepatic encephalopathyCNS, central nervous systemCr, creatineCSF, cerebrospinal fluidDTI, diffusion tensor imagingDWI, diffusion-weighted imagingFLAIR, fluid-attenuated inversion recoveryGln, glutamineGlx, sum of glutamine and glutamateGM, gray matterHE, hepatic encephalopathyIns, inositolin vivo magnetic resonance imagingin vivo magnetic resonance spectroscopyLac, lactateliver cirrhosisLPS, lipopolysaccharideMD, mean diffusivitymIns, myo-inositolMRI, magnetic resonance imagingMRS, magnetic resonance spectroscopyMT, magnetization transferMTR, MT ratioNMR, nuclear magnetic resonancePCA, portocaval anastomosistCho, total cholinetCr, total creatineTE, echo timeWM, white matter

Identifiers

PMID31360029
PMCPMC6637228
OpenAlexW2916317438

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.