ArticleJournal of assisted reproduction and genetics2019
Risk of ischemic placental disease is increased following in vitro fertilization with oocyte donation: a retrospective cohort study.
Article in Journal of assisted reproduction and genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- The risk for the development of hypertensive complications in oocyte donation pregnancy: a systematic review and individual participant data meta-analysis (DONOR IPD).Human reproduction update · 2026Pooled it
- Neonatal Health Following IVF: Own Versus Donor Material in Singleton and Multiple Pregnancies.Life (Basel, Switzerland) · 2025Article
- Risks of Placental Abruption and Preterm Delivery in Patients Undergoing Assisted Reproduction.JAMA network open · 2024Article
- Pregnancies through oocyte donation. A mini review of pathways involved in placental dysfunction.Frontiers in medicine · 2024Review
- Effects of Different Endometrial Preparation Regimens during IVF on Incidence of Ischemic Placental Disease for FET Cycles.Journal of clinical medicine · 2022Article
- PCOS and the risk of pre-eclampsia.Reproductive biomedicine online · 2022Article
- Article
- Multifoetal gestations mediate the effect of in vitro fertilisation (IVF) on ischaemic placental disease in autologous oocyte IVF more than donor oocyte IVF.Paediatric and perinatal epidemiology · 2022Article
- Placental Abnormalities and Placenta-Related Complications FollowingFrontiers in endocrinology · 2022Article
- Risk-Factor Based Lead Screening and Correlation with Blood Lead Levels in Pregnancy.Maternal and child health journal · 2022Article
- Angiogenic factors and prediction for ischemic placental disease in future pregnancies.Pregnancy hypertension · 2021Article
- Language Preference and Risk of Primary Cesarean Delivery: A Retrospective Cohort Study.Maternal and child health journal · 2021Article
- Elevated serum progesterone during in vitro fertilization treatment and the risk of ischemic placental disease.Pregnancy hypertension · 2021Article
- Association between in vitro fertilization and ischemic placental disease by gestational age.Fertility and sterility · 2020Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
purposeAssess the risk of ischemic placental disease (IPD) among in vitro fertilization (IVF; donor and autologous) pregnancies compared with non-IVF pregnancies.
methodsThis was a retrospective cohort study of deliveries from 2000 to 2015 at a tertiary hospital. The exposures, donor, and autologous IVF, were compared with non-IVF pregnancies and donor IVF pregnancies were also compared with autologous IVF pregnancies. The outcome was IPD (preeclampsia, placental abruption, small for gestational age (SGA), or intrauterine fetal demise due to placental insufficiency). We defined SGA as birthweight < 10th percentiles for gestational age and sex. A secondary analysis restricted SGA to < 3rd percentile.
resultsOf 69,084 deliveries in this cohort, 262 resulted from donor IVF and 3,501 from autologous IVF. Compared with non-IVF pregnancies, IPD was more common among donor IVF pregnancies (risk ratio (RR) = 2.9; 95% CI 2.5-3.4) and autologous IVF pregnancies (RR = 2.0; 95% CI 1.9-2.1), adjusted for age and parity. IVF pregnancies were more likely to be complicated by preeclampsia (donor RR = 3.8; 95% CI 2.8-5.0 and autologous RR = 2.2; 95% CI 2.0-2.5, adjusted for age, parity, and marital status), placental abruption (donor RR = 3.8; 95% CI 2.1-6.7 and autologous RR = 2.5; 95% CI 2.1-3.1, adjusted for age), and SGA (donor RR = 2.7; 95% CI 2.1-3.4 and autologous RR = 2.0; 95% CI 1.9-2.2, adjusted for age and parity). Results were similar when restricting SGA to < 3rd percentile.
conclusionPregnancies conceived using donor IVF and autologous IVF were at higher risk of IPD and its associated conditions than non-IVF pregnancies and associations were consistently stronger for donor IVF pregnancies.
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