ArticleAbdominal radiology (New York)2019
Does providing routine liver volume assessment add value when performing CT surveillance in cirrhotic patients?
Article in Abdominal radiology (New York), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Improvement of hepatic reserve and changes in liver and spleen volume after balloon-occluded retrograde transvenous obliteration.BMC gastroenterology · 2026Article
- Prognostic factors for peritoneovenous shunt placement for refractory ascites in liver cirrhosis.World journal of gastroenterology · 2025Article
- Impact of genetic variants linked to liver fat and liver volume on MRI-mapped body composition.JHEP reports : innovation in hepatology · 2025Article
- Benefits of Liver Volume and Serum Zinc Level Assessment for the Screening of Covert Hepatic Encephalopathy in Patients with Child-Pugh Class A Cirrhosis.Diagnostics (Basel, Switzerland) · 2024Article
- The impact of hepatic and splenic volumetric assessment in imaging for chronic liver disease: a narrative review.Insights into imaging · 2024Review
- Liver volume based prediction model for patients with hepatitis B virus-related acute-on-chronic liver failure.Journal of hepato-biliary-pancreatic sciences · 2022Article
- Nomogram based on spleen volume expansion rate predicts esophagogastric varices bleeding risk in patients with hepatitis B liver cirrhosis.Frontiers in surgery · 2022Article
- CT-scan Based Liver and Spleen Volume Measurement as a Prognostic Indicator for Patients with Cirrhosis.The American journal of the medical sciences · 2021Article
- Evaluation of Normal Adrenal Gland Volume and Morphometry and Relationship with Waist Circumference in an Adult Population Using Multidetector Computed Tomography.Sisli Etfal Hastanesi tip bulteni · 2021Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundThe measurement of liver volume (LV) is considered to be an effective prognosticator for postoperative liver failure in patients undergoing hepatectomy. It is unclear whether LV can be used to predict mortality in cirrhotic patients.
methodsWe enrolled 584 consecutive cirrhotic patients who underwent computerized topography (CT) of the abdomen for hepatocellular carcinoma surveillance and 50 age, gender, race, and BMI-matched controls without liver disease. Total LV (TLV), functional LV (FLV), and segmental liver volume (in cm
resultsCirrhotic subjects had significantly lower TLV, FLV, and segmental (all except for segments 1, 6, 7) volume when compared to controls. Subjects presenting with hepatic encephalopathy had significantly lower TLV and FLV than those without HE (p = 0.002). During the median follow-up of 1145 days, 112 (19%) subjects were transplanted and 131 (23%) died. TLV and FLV for those who survived were significantly higher than those who were transplanted or dead (TLV:1740 vs. 1529 vs. 1486, FLV 1691 vs. 1487 vs. 1444, p < 0.0001). In the Cox regression model, age, MELD score, TLV, or FLV were independent predictors of mortality.
conclusionBaseline liver volume is an independent predictor of mortality in subjects with cirrhosis. Therefore, it may be useful to provide these data while performing routine surveillance CT scan as an important added value. Further studies are needed to validate these findings and to better understand their clinical utility.
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