ArticleScientific reports2019
Treatment of splenic flexure colon cancer: a comparison of three different surgical procedures: Experience of a high volume cancer center.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The emperor has no clothes-the need for standardized anatomical segment definitions in the management of colon cancer.International journal of colorectal disease · 2025Pooled it
- Short- and long-term outcomes after surgical treatment of 5918 patients with splenic flexure colon cancer by extended right colectomy, segmental colectomy and left colectomy: a systematic review and meta-analysis.Frontiers in oncology · 2024Pooled it
- Comparative Efficacy and Long-Term Oncological Safety of Extended Right Hemicolectomy Versus Left Colectomy for Splenic Flexure Adenocarcinoma: A Systematic Review and Meta-Analysis.Cancer control : journal of the Moffitt Cancer CenterPooled it
- Efficacy and Safety of rCCK96-104PE38 Targeted Drug in the General Surgical Treatment of Colon Cancer.BioMed research international · 2022Trial
- Robotic Segmental Mid-Transverse Colectomy Guided by Intraoperative Frozen Section of Ileocolic Lymph Nodes.Annals of surgical oncology · 2026Article
- When colon cancer crosses boundaries: acute abdomen from direct pancreatic infiltration by a splenic flexure tumour.Journal of surgical case reports · 2026Article
- Comparison of the short-term and mid-term outcomes between robot-assisted and laparoscopic surgery for splenic flexure colon cancer.Surgery today · 2026Article
- Decision-making in emergency colorectal surgery for cancer.Annals of medicine and surgery (2012) · 2026Article
- Short- and Long-Term Outcomes of Laparoscopic Segmental Left Colectomy for Splenic Flexure Colon Cancer: A Multicenter Propensity Score-Matched Analysis from the Catholic Colorectal Group.Journal of clinical medicine · 2026Article
- Review
- Splenic flexure colon cancer may represent a distinct prognostic subtype associated with elevated systemic inflammation and impaired nutritional status.Frontiers in immunology · 2026Article
- Surgical management of splenic flexure colonic malignancy.World journal of gastrointestinal surgery · 2025Review
- Review
- Improved outcomes with cyanoacrylate glue for ileocolic anastomosis in right colectomy: a multicenter study.Annals of coloproctology · 2025Article
- Splenic flexure adenocarcinoma: A national cohort analysis of extent of surgical resection and outcomes.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2024Article
- Extended procedure has no oncological benefits over segmental resection in the treatment of non-metastatic splenic flexure colon cancer, a population-based cohort study and a single center's decade-long experience.Updates in surgery · 2024Article
- Treatment Differences for Splenic Flexure Cancers in Saudi Arabia: A Cross-Sectional Study.Cureus · 2024Article
- SF-CORNER (splenic flexure colorectal cancer): an international survey of operative approaches and outcomes for cancers of the splenic flexure.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2024Article
- Imaging Features of Main Hepatic Resections: The Radiologist Challenging.Journal of personalized medicine · 2023Review
- Re-interpreting mesenteric vascular anatomy on 3D virtual and/or physical models, part II: anatomy of relevance to surgeons operating splenic flexure cancer.Surgical endoscopy · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extended right or left hemicolectomy are the most common surgical treatments for splenic flexure colon cancer. Extended resection (including distal pancreasectomy and/or splenectomy), has been often indicated for the treatment for the splenic flexure cancer, because the lymphatic drainage at this site is poorly defined and assumed as heterogeneous. Between January 2006 and May 2016, 103 patients with splenic flexure colon cancer were enrolled in the study. We evaluated the clinicopathological findings and outcomes of all patients and associated them to the different surgical treatment. Out of 103 selected cases an extended right hemicolectomy was performed in 22 (21.4%) patients, an extended left hemicolectomy in 24 (23.3%) patients, a segmental resection of the splenic flexure in 57 (55.3%) patients; the combined resection of adjacent organs showing tumor adherence was carried out in 11 (10.7%) patients. The tumor infiltrated near organs (T4) in 5 patients. No significant differences in complications were found among the three groups. In all groups no differences were found in the total number of harvested lymphnodes. After a median follow-up of 42 months, 30 recurrences and 19 deaths occurred (12 for tumor progression). There was no difference in overall and progression free survival among the three different surgical treatments. According to our results, the partial resection of splenic flexure was not associated with a worse prognosis and it was leading for a satisfactory oncological outcome. It is our opinion that the extended surgery is seldomly indicated to cure splenic flexure cancer.
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