Evidence map›Paper›PMID 31358763›Full record

ArticleNature communications2019

Time-resolved NMR monitoring of tRNA maturation.

Pierre Barraud, Alexandre Gato, Matthias Heiss, Marjorie Catala, Stefanie Kellner, Carine Tisné

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 92 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. RNase 4 improves bottom-up modification mapping ofbioRxiv : the preprint server for biology · 2026
    Article
  5. Pseudouridylation landscape across 42bioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Article
  8. Optimized tRNA structure-seq reveals robust tRNA secondary structures inbioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. TRMT1L-catalyzed mCell reports · 2025
    Article
  16. Article
  17. Imino chemical shift assignments of tRNABiomolecular NMR assignments · 2024
    Article
  18. Article
  19. TRMT1L-catalyzed mbioRxiv : the preprint server for biology · 2024
    Article
  20. Conserved 5-methyluridine tRNA modification modulates ribosome translocation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Pierre BarraudExpression génétique microbienne, UMR 8261, CNRS, Université de Paris, Institut de biologie physico-chimique, 13 rue Pierre et Marie Curie, 75005, Paris, France. pierre.barraud@cnrs.fr.ORCID http://orcid.org/0000-0003-4460-8360
Alexandre GatoExpression génétique microbienne, UMR 8261, CNRS, Université de Paris, Institut de biologie physico-chimique, 13 rue Pierre et Marie Curie, 75005, Paris, France.
Matthias HeissDepartment of Chemistry, Ludwig Maximilians University Munich, Butenandtstr. 5-13, 81377, Munich, Germany.
Marjorie CatalaExpression génétique microbienne, UMR 8261, CNRS, Université de Paris, Institut de biologie physico-chimique, 13 rue Pierre et Marie Curie, 75005, Paris, France.
Stefanie KellnerDepartment of Chemistry, Ludwig Maximilians University Munich, Butenandtstr. 5-13, 81377, Munich, Germany.ORCID http://orcid.org/0000-0003-3224-7502
Carine TisnéExpression génétique microbienne, UMR 8261, CNRS, Université de Paris, Institut de biologie physico-chimique, 13 rue Pierre et Marie Curie, 75005, Paris, France. carine.tisne@cnrs.fr.ORCID http://orcid.org/0000-0001-5534-4650
Centre National de la Recherche Scientifique · FRLudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the biological importance of post-transcriptional RNA modifications in gene expression is widely appreciated, methods to directly detect their introduction during RNA biosynthesis are rare and do not easily provide information on the temporal nature of events. Here, we introduce the application of NMR spectroscopy to observe the maturation of tRNAs in cell extracts. By following the maturation of yeast tRNA

Indexed as

RNA Processing, Post-TranscriptionalBase SequenceMagnetic Resonance SpectroscopyModels, MolecularNucleic Acid ConformationRNA, TransferRNA, Transfer, PheSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTime FactorstRNA MethyltransferasesRNA, TransferRNA, Transfer, PheSaccharomyces cerevisiae ProteinstRNA Methyltransferases

Identifiers

PMID31358763
PMCPMC6662845
OpenAlexW2965220844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.