Evidence map›Paper›PMID 31358733›Full record

Trial reportBlood cancer journal2019

Phase I/II trial of bendamustine, ixazomib, and dexamethasone in relapsed/refractory multiple myeloma.

Binod Dhakal, Anita D'Souza, Mehdi Hamadani, Carlos Arce-Lara, Katrina Schroeder, Saurabh Chhabra, Nirav N Shah, Katelyn Gauger, Taylor Keaton, Marcelo Pasquini and 1 more

Abstract readClinical Trial, Phase IClinical Trial, Phase II
In one paragraph

Trial report in Blood cancer journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Targeting ubiquitination in disease and therapy.Signal transduction and targeted therapy · 2025
    Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Emerging agents and regimens for multiple myeloma.Journal of hematology & oncology · 2020
    Review
  9. Review
  10. Review
  11. The role of ubiquitination in tumorigenesis and targeted drug discovery.Signal transduction and targeted therapy · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Binod DhakalDivision of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI, USA. bdhakal@mcw.edu.
Anita D'SouzaDivision of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.
Mehdi HamadaniDivision of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.
Carlos Arce-LaraDivision of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.
Katrina SchroederDivision of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.
Saurabh ChhabraDivision of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.
Nirav N ShahDivision of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.
Katelyn GaugerDivision of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.
Taylor KeatonDivision of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.
Marcelo PasquiniDivision of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.
Parameswaran HariDivision of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this phase I/II trial, BID, bendamustine (70, 80, or 90 mg/m

Indexed as

AdultAgedAntineoplastic Combined Chemotherapy ProtocolsBendamustine HydrochlorideBoron CompoundsDexamethasoneDrug Resistance, NeoplasmFemaleGlycineHumansMaleMiddle AgedMultiple MyelomaNeoplasm Recurrence, LocalPatient SafetyTreatment OutcomeBendamustine HydrochlorideBoron CompoundsDexamethasoneGlycineixazomib

Identifiers

PMID31358733
PMCPMC6663939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.