Evidence map›Paper›PMID 31358651›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Stimulation of the Posterior Cingulate Cortex Impairs Episodic Memory Encoding.

Vaidehi S Natu, Jui-Jui Lin, Alexis Burks, Akshay Arora, Michael D Rugg, Bradley Lega

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 93 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Vaidehi S NatuDepartment of Neurological Surgery, University of Texas Southwestern Medical Center, Dallas, Texas 75390, and vaidehi.natu@utsouthwestern.edu.
Jui-Jui LinDepartment of Neurological Surgery, University of Texas Southwestern Medical Center, Dallas, Texas 75390, and.ORCID 0000-0002-2215-9245
Alexis BurksDepartment of Neurological Surgery, University of Texas Southwestern Medical Center, Dallas, Texas 75390, and.
Akshay AroraDepartment of Neurological Surgery, University of Texas Southwestern Medical Center, Dallas, Texas 75390, and.
Michael D RuggCenter for Vital Longevity, University of Texas at Dallas, Texas 75080.ORCID 0000-0002-0397-5749
Bradley LegaDepartment of Neurological Surgery, University of Texas Southwestern Medical Center, Dallas, Texas 75390, and.
Neurological Surgery · USSouthwestern Medical Center · USThe University of Texas at Dallas · US

Funding

Using deep brain stimulation of the parietal cortex to investigate the electrophysiology of human episodic memoryR01NS107357 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI Bradley C Lega · 2018 to 2026
$3.6M
NINDS NIH HHS R01 NS107357
6 · The paper itself

Abstract

Neuroimaging experiments implicate the posterior cingulate cortex (PCC) in episodic memory processing, making it a potential target for responsive neuromodulation strategies outside of the hippocampal network. However, causal evidence for the role that PCC plays in memory encoding is lacking. In human female and male participants (

Indexed as

Memory, EpisodicAdultDeep Brain StimulationFemaleGamma RhythmGyrus CinguliHippocampusHumansMaleMiddle AgedSeizuresdeep brain stimulationepisodic memoryfunctional connectivityhippocampusposterior cingulate cortexstereotactic electroencephalography

Identifiers

PMID31358651
PMCPMC6733540
OpenAlexW2964813937

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.