Evidence map›Paper›PMID 31358644›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Dynamic colocalization of 2 simultaneously active

James Budzak, Louise E Kerry, Aris Aristodemou, Belinda S Hall, Kathrin Witmer, Manish Kushwaha, Carys Davies, Megan L Povelones, Jacquelyn R McDonald, Aakash Sur and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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  13. DNA Double-Strand Breaks: A Double-Edged Sword for Trypanosomatids.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

James BudzakDepartment of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Louise E KerryDepartment of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Aris AristodemouDepartment of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Belinda S HallDepartment of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Kathrin WitmerDepartment of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Manish KushwahaDepartment of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Carys DaviesDepartment of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Megan L PovelonesDepartment of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom.
Jacquelyn R McDonaldCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109.
Aakash SurCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109.
Peter J MylerCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109.
Gloria RudenkoDepartment of Life Sciences, Imperial College London, SW7 2AZ London, United Kingdom; gloria.rudenko@imperial.ac.uk.ORCID 0000-0003-1884-4933
Imperial College London · GBInfectious Disease Research Institute · US

Funding

Base J and transcription termination in LeishmaniaR01AI103858 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI MYLER, PETER JOHN · 2013 to 2017
$2.8M
Biotechnology and Biological Sciences Research CouncilNIAID NIH HHS R01 AI103858Wellcome Trust 095161Wellcome Trust 212211/Z/18/Z
6 · The paper itself

Abstract

Monoallelic exclusion ensures that the African trypanosome

Indexed as

Cell LineEpigenesis, GeneticProtein TransportTranscription, GeneticTrypanosoma brucei bruceiVariant Surface Glycoproteins, TrypanosomaVariant Surface Glycoproteins, Trypanosomaantigenic variationepigeneticsmonoallelic exclusionRNA polymerase Ivariant surface glycoprotein

Identifiers

PMID31358644
PMCPMC6697882
OpenAlexW2965545141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.