Evidence map›Paper›PMID 31358631›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

High-speed AFM reveals subsecond dynamics of cardiac thin filaments upon Ca

Oleg S Matusovsky, Alf Mansson, Malin Persson, Yu-Shu Cheng, Dilson E Rassier

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
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  8. Article
  9. Mechanical contribution to muscle thin filament activation.The Journal of biological chemistry · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Oleg S MatusovskyDepartment of Kinesiology and Physical Education, McGill University, Montreal, QC H2W 1S4, Canada.ORCID 0000-0002-0824-9260
Alf ManssonDepartment of Chemistry and Biomedical Sciences, Linnaeus University, SE-391 82 Kalmar, Sweden.ORCID 0000-0002-5889-7792
Malin PerssonDepartment of Kinesiology and Physical Education, McGill University, Montreal, QC H2W 1S4, Canada.
Yu-Shu ChengDepartment of Kinesiology and Physical Education, McGill University, Montreal, QC H2W 1S4, Canada.
Dilson E RassierDepartment of Kinesiology and Physical Education, McGill University, Montreal, QC H2W 1S4, Canada; dilson.rassier@mcgill.ca.
McGill University · CALinnaeus University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-speed atomic force microscopy (HS-AFM) can be used to study dynamic processes with real-time imaging of molecules within 1- to 5-nm spatial resolution. In the current study, we evaluated the 3-state model of activation of cardiac thin filaments (cTFs) isolated as a complex and deposited on a mica-supported lipid bilayer. We studied this complex for dynamic conformational changes 1) at low and high [Ca

Indexed as

Actin CytoskeletonActinsAnimalsCalciumLipid BilayersModels, MolecularMolecular ImagingMuscle ContractionMuscle, SkeletalMyocardiumMyosinsMyosin SubfragmentsProtein BindingRabbitsSarcomeresTropomyosinActinsCalciumLipid BilayersMyosinsMyosin SubfragmentsTropomyosinTroponintroponin-tropomyosin complexHS-AFMmuscle contractionthin filaments

Identifiers

PMID31358631
PMCPMC6697793
OpenAlexW2965544134

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.