Evidence map›Paper›PMID 31358615›Full record

ArticleJournal of bacteriology2019

The Cyclopropane Fatty Acid Synthase Mediates Antibiotic Resistance and Gastric Colonization of Helicobacter pylori.

Xueqing Jiang, Yuanyuan Duan, Boshen Zhou, Qiaoqiao Guo, Haihong Wang, Xudong Hang, Liping Zeng, Jia Jia, Hongkai Bi

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Unusual Phospholipids fromJournal of the American Chemical Society · 2025
    Article
  8. Article
  9. Roles of theFrontiers in cellular and infection microbiology · 2025
    Article
  10. Article
  11. Article
  12. Fatty acids ofMicrobiology spectrum · 2024
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Cyclopropane Fatty Acids Are Important forInfection and immunity · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xueqing Jiang *Department of Pathogen Biology, Jiangsu Key Laboratory of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, China.
Yuanyuan Duan *Laboratory Center for Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu, China.
Boshen ZhouDepartment of Pathogen Biology, Jiangsu Key Laboratory of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, China.
Qiaoqiao GuoGuangdong Provincial Key Laboratory of Protein Function and Regulation in Agricultural Organisms, College of Life Sciences, South China Agricultural University, Guangzhou, Guangdong, China.
Haihong WangGuangdong Provincial Key Laboratory of Protein Function and Regulation in Agricultural Organisms, College of Life Sciences, South China Agricultural University, Guangzhou, Guangdong, China.
Xudong HangDepartment of Pathogen Biology, Jiangsu Key Laboratory of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, China.
Liping ZengDepartment of Pathogen Biology, Jiangsu Key Laboratory of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, China.
Jia JiaDepartment of Pathogen Biology, Jiangsu Key Laboratory of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, China.
Hongkai BiDepartment of Pathogen Biology, Jiangsu Key Laboratory of Pathogen Biology, Nanjing Medical University, Nanjing, Jiangsu, China hkbi@njmu.edu.cn.
Nanjing Medical University · CNSouth China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclopropane fatty acids (CFAs) are synthetized by the addition of a methylene group from

Indexed as

Drug Resistance, MicrobialAminesAnimalsBacterial ProteinsCyclopropanesFatty AcidsFemaleGene Expression Regulation, BacterialGene Expression Regulation, EnzymologicHelicobacter InfectionsHelicobacter pyloriHumansMethyltransferasesMiceVirulence FactorsAminesBacterial Proteinscyclopropane fatty acidsCyclopropanescyclopropane synthetaseFatty AcidsMethyltransferasesoctylamineVirulence Factorsacid resistancecyclopropane fatty aciddrug targetHelicobacter pylorimouse gastric colonization

Identifiers

PMID31358615
PMCPMC6755722
OpenAlexW2964378268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.