Evidence map›Paper›PMID 31358587›Full record

ArticleAntimicrobial agents and chemotherapy2019

Treatment by Posaconazole Tablets, Compared to Posaconazole Suspension, Does Not Reduce Variability of Posaconazole Trough Concentrations.

Elodie Gautier-Veyret, Léa Bolcato, Matthieu Roustit, Stéphanie Weiss, Julia Tonini, Marie-Pierre Brenier-Pinchart, Muriel Cornet, Anne Thiebaut-Bertrand, Françoise Stanke-Labesque

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Review
  6. Article
  7. A Review of Population Pharmacokinetic Models of Posaconazole.Drug design, development and therapy · 2022
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elodie Gautier-VeyretUniversité Grenoble Alpes, Inserm, CHU Grenoble Alpes, Grenoble, France egautier@chu-grenoble.fr.ORCID 0000-0002-5846-3847
Léa BolcatoLaboratoire de Pharmacologie, Pharmacogénétique et Toxicologie, CHU Grenoble Alpes, Grenoble, France.
Matthieu RoustitUniversité Grenoble Alpes, Inserm, CHU Grenoble Alpes, Grenoble, France.
Stéphanie WeissLaboratoire de Pharmacologie, Pharmacogénétique et Toxicologie, CHU Grenoble Alpes, Grenoble, France.
Julia ToniniLaboratoire de Pharmacologie, Pharmacogénétique et Toxicologie, CHU Grenoble Alpes, Grenoble, France.
Marie-Pierre Brenier-PinchartParasitologie-Mycologie, CHU Grenoble Alpes, Grenoble, France.
Muriel CornetUniversité Grenoble Alpes, CNRS, CHU Grenoble Alpes, Grenoble INP, Grenoble, France.ORCID 0000-0003-4155-3675
Anne Thiebaut-BertrandDépartement d'Hématologie, CHU Grenoble Alpes, Grenoble, France.
Françoise Stanke-LabesqueUniversité Grenoble Alpes, Inserm, CHU Grenoble Alpes, Grenoble, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The delayed-release tablet formulation of posaconazole (POS-tab) results in higher plasma POS trough concentrations (C

Indexed as

Hematopoietic Stem Cell TransplantationAdministration, OralAdultAgedAge FactorsAnalysis of VarianceAntifungal AgentsDiarrheaDrug Administration ScheduleDrug MonitoringFemaleHematologic NeoplasmsHumansMaleMiddle AgedMycosesAntifungal AgentsposaconazoleSuspensionsTabletsTriazoleshematopoietic stem cell transplantationposaconazoletherapeutic drug monitoringtrough concentrationvariability

Identifiers

PMID31358587
PMCPMC6761514

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.