Evidence map›Paper›PMID 31358568›Full record

ArticleInfection and immunity2019

Interleukin-10 (IL-10) Produced by Mutant Toxic Shock Syndrome Toxin 1 Vaccine-Induced Memory T Cells Downregulates IL-17 Production and Abrogates the Protective Effect against Staphylococcus aureus Infection.

Kouji Narita, Dong-Liang Hu, Krisana Asano, Akio Nakane

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Acellular Pertussis Vaccines Induce CD8European journal of immunology · 2025
    Article
  2. Review
  3. Article
  4. Article
  5. Conserved moonlighting protein pyruvate dehydrogenase induces robust protection againstProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Transcriptome Architecture of Osteoblastic Cells Infected WithFrontiers in cellular and infection microbiology · 2022
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kouji NaritaDepartment of Microbiology and Immunology, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.
Dong-Liang HuDepartment of Microbiology and Immunology, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.
Krisana AsanoDepartment of Microbiology and Immunology, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.
Akio NakaneDepartment of Microbiology and Immunology, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan a27k03n0@hirosaki-u.ac.jp.
Hirosaki University · JPKitasato University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development of long-term memory is crucial for vaccine-induced adaptive immunity against infectious diseases such as

Indexed as

AnimalsAntibodies, NeutralizingBacterial ToxinsCloning, MolecularEnterotoxinsEscherichia coliGene ExpressionGenetic VectorsImmunologic MemoryInterleukin-10Interleukin-17MiceMice, Inbred C57BLMice, KnockoutRecombinant ProteinsStaphylococcal InfectionsAntibodies, NeutralizingBacterial Toxinsenterotoxin F, StaphylococcalEnterotoxinsIL10 protein, mouseIl17a protein, mouseInterleukin-10Interleukin-17Recombinant ProteinsStaphylococcal VaccinesSuperantigensVaccines, SyntheticIL-10IL-17Staphylococcus aureusTh17toxic shock syndrome toxin 1

Identifiers

PMID31358568
PMCPMC6759301
OpenAlexW2966323301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.