Evidence map›Paper›PMID 31358566›Full record

SynthesisOccupational and environmental medicine2019

Parental occupational exposure to low-frequency magnetic fields and risk of leukaemia in the offspring: findings from the Childhood Leukaemia International Consortium (CLIC).

Madar Talibov, Ann Olsson, Helen Bailey, Friederike Erdmann, Catherine Metayer, Corrado Magnani, Eleni Petridou, Anssi Auvinen, Logan Spector, Jacqueline Clavel and 10 more

Open access · hybridAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Occupational and environmental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 14 institutions in 11 countries.

Madar TalibovSection of Environment and Radiation, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0002-6548-358X
Ann OlssonSection of Environment and Radiation, International Agency for Research on Cancer, Lyon, France.
Helen BaileyTelethon Kids Institute, University of Western Australia, Perth, Australia.
Friederike ErdmannSection of Environment and Radiation, International Agency for Research on Cancer, Lyon, France.
Catherine MetayerSchool of Public Health, University of California, Berkeley, California, USA.
Corrado MagnaniDipartimento di Medicina Traslazionale, SCDU Epidemiologia del Tumori, Universita' del Piemonte Orientale, Novara, Italy.
Eleni PetridouDepartment of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens & Clinical Epidemiology Unit, Athens, Greece.
Anssi AuvinenFaculty of Social/Health Sciences, Tampereen yliopisto, Tampere, Finland.
Logan SpectorDivision of Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
Jacqueline ClavelU1018, INSERM, Villejuif, France.
Eve RomanEpidemiology and Cancer Statistics Group, Department of Health Sciences, University of York, York, UK.
John DockertyDepartment of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand.
Atte NikkiläFaculty of Medicine and Biosciences, University of Tampere, Tampere, Finland.
Olli LohiTampere Center for Child Health Research, Tampere University Hospital and University of Tampere, Tampere, Finland.
Alice KangSchool of Public Health, University of California, Berkeley, California, USA.
Theodora PsaltopoulouDepartment of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens & Clinical Epidemiology Unit, Athens, Greece.
Lucia MiligiEnvironmental and Occuaptional Epidemiology Unit, ISPO Cancer Prevention and Research Institute, Florence, Italy.
Javier VilaBarcelona Institute for Global Health (ISGlobal), Barcelona, Spain.
Elisabeth CardisBarcelona Institute for Global Health (ISGlobal), Barcelona, Spain.
Joachim SchüzSection of Environment and Radiation, International Agency for Research on Cancer, Lyon, France.
Centre international de recherche sur le cancer · FRBarcelona Institute for Global Health · ESNational and Kapodistrian University of Athens · GRTampere University · FIUniversity of California, Berkeley · USDanish Cancer Society · DKPiedmont Reference Center for Epidemiology and Cancer Prevention · ITTampere University Hospital · FIThe Kids Research Institute Australia · AUUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITUniversité Paris-Sud · FRUniversity of Minnesota · USUniversity of Otago · NZUniversity of York · GB

Funding

World Health Organization 001
6 · The paper itself

Abstract

objectivesPreviously published studies on parental occupational exposure to extremely low-frequency magnetic fields (ELF-MF) and risk of acute lymphoblastic leukaemia (ALL) and acute myeloid leukaemia (AML) in their offspring were inconsistent. We therefore evaluated this question within the Childhood Leukemia International Consortium.

methodsWe pooled 11 case-control studies including 9723 childhood leukaemia cases and 17 099 controls. Parental occupational ELF-MF exposure was estimated by linking jobs to an ELF-MF job-exposure matrix (JEM). Logistic regression models were used to estimate ORs and 95% CIs in pooled analyses and meta-analyses.

resultsORs from pooled analyses for paternal ELF-MF exposure >0.2 microtesla (µT) at conception were 1.04 (95% CI 0.95 to 1.13) for ALL and 1.06 (95% CI 0.87 to 1.29) for AML, compared with ≤0.2 µT. Corresponding ORs for maternal ELF-MF exposure during pregnancy were 1.00 (95% CI 0.89 to 1.12) for ALL and 0.85 (95% CI 0.61 to 1.16) for AML. No trends of increasing ORs with increasing exposure level were evident. Furthermore, no associations were observed in the meta-analyses.

conclusionsIn this large international dataset applying a comprehensive quantitative JEM, we did not find any associations between parental occupational ELF-MF exposure and childhood leukaemia.

Indexed as

AdolescentCase-Control StudiesChildChild, PreschoolFemaleHumansInfantLeukemia, Myeloid, AcuteMagnetic FieldsMaleMaternal ExposureOccupational ExposurePaternal ExposurePrecursor Cell Lymphoblastic Leukemia-LymphomaPregnancyPrenatal Exposure Delayed Effectsacute lymphoblastic leukemiaacute myeloid leukemiacase-control studyelf-mfoccupation

Identifiers

PMID31358566
PMCPMC6817988
OpenAlexW2966434476

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.