Evidence map›Paper›PMID 31358536›Full record

ArticleDevelopment (Cambridge, England)2019

Dchs1-Fat4 regulation of osteogenic differentiation in mouse.

Ivan Crespo-Enriquez, Tina Hodgson, Sana Zakaria, Erika Cadoni, Mittal Shah, Stephen Allen, Ayman Al-Khishali, Yaopan Mao, Angela Yiu, Jonna Petzold and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Search for Ancient Selection Traces in Faverolle Chicken Breed (Animals : an open access journal from MDPI · 2025
    Article
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  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. EctomesenchymalFrontiers in genetics · 2023
    Article
  16. Article
  17. Cranium growth, patterning and homeostasis.Development (Cambridge, England) · 2022
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Ivan Crespo-EnriquezCentre for Craniofacial and Regenerative Biology, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, Floor 27, Guy's Tower, London SE1 9RT, UK.ORCID 0000-0003-2967-4554
Tina HodgsonCentre for Craniofacial and Regenerative Biology, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, Floor 27, Guy's Tower, London SE1 9RT, UK.
Sana ZakariaCentre for Craniofacial and Regenerative Biology, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, Floor 27, Guy's Tower, London SE1 9RT, UK.
Erika CadoniCentre for Craniofacial and Regenerative Biology, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, Floor 27, Guy's Tower, London SE1 9RT, UK.
Mittal ShahComparative Biomedical Sciences, Royal Veterinary College, Camden, London, NW1 0TU, UK.
Stephen AllenComparative Biomedical Sciences, Royal Veterinary College, Camden, London, NW1 0TU, UK.
Ayman Al-KhishaliCentre for Craniofacial and Regenerative Biology, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, Floor 27, Guy's Tower, London SE1 9RT, UK.
Yaopan MaoWaksman Institute and Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08854, USA.
Angela YiuCentre for Craniofacial and Regenerative Biology, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, Floor 27, Guy's Tower, London SE1 9RT, UK.
Jonna PetzoldCentre for Craniofacial and Regenerative Biology, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, Floor 27, Guy's Tower, London SE1 9RT, UK.
Guillermo Villagomez-OleaCentre for Craniofacial and Regenerative Biology, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, Floor 27, Guy's Tower, London SE1 9RT, UK.
Andrew A PitsillidesComparative Biomedical Sciences, Royal Veterinary College, Camden, London, NW1 0TU, UK.
Kenneth D IrvineWaksman Institute and Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08854, USA.
Philippa Francis-WestORCID 0000-0001-5179-5892
King's College London · GBRoyal Veterinary College · GBRutgers, The State University of New Jersey · US

Funding

Growth regulation by the Fat signaling pathwayR01GM078620 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI IRVINE, KENNETH D · 2007 to 2018
$3.3M
Biotechnology and Biological Sciences Research Council BB/K008668/1Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM078620
6 · The paper itself

Abstract

In human, mutations of the protocadherins FAT4 and DCHS1 result in Van Maldergem syndrome, which is characterised, in part, by craniofacial abnormalities. Here, we analyse the role of Dchs1-Fat4 signalling during osteoblast differentiation in mouse. We show that

Indexed as

Abnormalities, MultipleAnimalsAnimals, NewbornCadherinsCell DifferentiationCells, CulturedCraniofacial AbnormalitiesDisease Models, AnimalEmbryo, MammalianFemaleFoot Deformities, CongenitalHand Deformities, CongenitalHumansIntellectual DisabilityJoint InstabilityMiceCadherinsDchs1 protein, mouseFat4 protein, mouseDchs1-Fat4OsteoblastRunx2Yap/Taz

Identifiers

PMID31358536
PMCPMC7376788
OpenAlexW2965188138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.