Evidence map›Paper›PMID 31357981›Full record

ArticleBMC public health2019

The impact of screening on the survival of colorectal cancer in Shanghai, China: a population based study.

Xiaopan Li, Yi Zhou, Zheng Luo, Yi'an Gu, Yichen Chen, Chen Yang, Jing Wang, Shaotan Xiao, Qiao Sun, Mengcen Qian and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaopan LiSchool of Public Health, Fudan University, 130 Dong'an Rd, Shanghai, 200032, China.
Yi ZhouCenter for Disease Control and Prevention, Pudong New Area, Shanghai, 200136, China.
Zheng LuoShanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Pudong New Area, Shanghai, 201318, China.
Yi'an GuDepartment of epidemiology, Columbia University, New York, NY, USA.
Yichen ChenCenter for Disease Control and Prevention, Pudong New Area, Shanghai, 200136, China.
Chen YangCenter for Disease Control and Prevention, Pudong New Area, Shanghai, 200136, China.
Jing WangCenter for Disease Control and Prevention, Pudong New Area, Shanghai, 200136, China.
Shaotan XiaoCenter for Disease Control and Prevention, Pudong New Area, Shanghai, 200136, China.
Qiao SunCenter for Disease Control and Prevention, Pudong New Area, Shanghai, 200136, China.
Mengcen QianSchool of Public Health, Fudan University, 130 Dong'an Rd, Shanghai, 200032, China. qianmengcen@fudan.edu.cn.
Genming ZhaoSchool of Public Health, Fudan University, 130 Dong'an Rd, Shanghai, 200032, China. gmzhao@shmu.edu.cn.ORCID http://orcid.org/0000-0002-9625-478X

Funding

Foundation of Shanghai Municipal Commission of Health and Family Planning 201540407Fund of Key Discipline Construction in Pudong New Area Health System PWZxk2017-28National Key R & D Program of China 2017YFC09070000Shanghai Municipal Health Bureau 20164Y0083the Young Medical Talents Training Program of the Pudong Health Bureau of Shanghai PWRq2017-33
6 · The paper itself

Abstract

backgroundShanghai is one of the earliest cities in developing countries to introduce an organized colorectal screening program for its residents to fight against the rising disease burden of colorectal cancer (CRC). This study aims to investigate the impact of the Shanghai screening program implemented in 2013 on the survival rates of CRC patients.

methodsWe calculated up to 5-year survival rates for 18,592 CRC patients from a representative district of Shanghai during 2002-2016, using data from the Shanghai Cancer Registry. We performed joinpoint regressions to examine temporal changes in the trends of the CRC survival rates. We then conducted Kaplan-Meier and Cox proportional hazards modelling to study the association of the survival rates with screening behaviors of the patients. In all the model specifications, we took into account the gender, age and TNM stage at diagnosis, and level of treatment hospital of the patients.

resultsWe find that the annual percentage changes of the survival rates increased faster after somewhere around 2013, however, the differential trends were not significant. Results from the Cox multivariate regression analysis suggest that patients who did not participate in the screening program showed significantly lower cancer-specific survival (hazard ratio (HR) = 1.46; 95% confidence interval (CI): 1.12-1.91) and all-causes survival (HR = 1.37; 95% CI: 1.05-1.77), compared to those who did. Among program participants, delayed colonoscopy was associated with poor cancer-specific survival (hazard ratio (HR) = 2.93; 95% confidence interval (CI): 1.64-5.23) and all-causes survival (HR = 3.29; 95% CI: 1.85-5.84).

conclusionScreening participation and high level of colonoscopy compliance can improve the survival of CRC participants.

Indexed as

AgedChinaColonoscopyColorectal NeoplasmsEarly Detection of CancerFemaleHumansMaleMiddle AgedPatient ComplianceProportional Hazards ModelsRegistriesSurvival RateColorectal cancerComplianceScreeningSurvival

Identifiers

PMID31357981
PMCPMC6664771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.